Literature DB >> 30781997

Hesperidin improves the follicular development in 3D culture of isolated preantral ovarian follicles of mice.

Hamed Shoorei1,2, Majid Banimohammad3, Maziar M Kebria4, Mohammad Afshar2, Mohammad Mh Taheri2, Majid Shokoohi1, Mohammad Sg Farashah1, Mina Eftekharzadeh5, Omid Akhiani6, Robert Gaspar6,7, Hamidreza Pazoki-Toroudi3,8.   

Abstract

IMPACT STATEMENT: It has been stated that hesperidin has many pharmacological effects, such as anti-inflammatory and antioxidant effects, antimicrobial activity, and anti-carcinogenic activity; but hesperidin and its derivatives have been under investigation as anti-fertility factors for a very long time. However, our results show that hesperidin can improve mice follicular growth and maturation during in vitro 3D culture. Hesperidin as an antioxidant factor could enhance the mRNA expression levels of two important genes involved in folliculogenesis, PCNA, and FSH-R. Our results prove for the first time that hesperidin not only has deleterious effects on follicular development but can also increase rates of in vitro fertilization and embryo development.

Entities:  

Keywords:  Ovarian follicle culture; gene expression; hesperidin; hormones; in vitro fertilization; in vitro maturation

Mesh：

Substances：

Year:  2019        PMID： 30781997      PMCID： PMC6488865          DOI： 10.1177/1535370219831615

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN： 1535-3699


  39 in total

1.  A new mathematical model for relative quantification in real-time RT-PCR.

Authors:  M W Pfaffl
Journal:  Nucleic Acids Res       Date:  2001-05-01       Impact factor: 16.971

2.  Cytoplasmic fragmentation in activated eggs occurs in the cytokinetic phase of the cell cycle, in lieu of normal cytokinesis, and in response to cytoskeletal disorder.

Authors:  Mina Alikani; Tim Schimmel; Steen M Willadsen
Journal:  Mol Hum Reprod       Date:  2005-04-29       Impact factor: 4.025

3.  Effect of Phosphorylated Hesperidin, a Hyaluronidase Inhibitor, on Fertility in the Rat.

Authors:  G J Martin; J M Beiler
Journal:  Science       Date:  1952-04-11       Impact factor: 47.728

Review 4.  Chemistry and pharmacology of the Citrus bioflavonoid hesperidin.

Authors:  A Garg; S Garg; L J Zaneveld; A K Singla
Journal:  Phytother Res       Date:  2001-12       Impact factor: 5.878

Review 5.  Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.

Authors:  Anita H Payne; Dale B Hales
Journal:  Endocr Rev       Date:  2004-12       Impact factor: 19.871

6.  Antioxidant activity of the flavonoid hesperidin in chemical and biological systems.

Authors:  Patricia Kelly Wilmsen; Dalla Santa Spada; Mirian Salvador
Journal:  J Agric Food Chem       Date:  2005-06-15       Impact factor: 5.279

Review 7.  Genetic control of early folliculogenesis in mice.

Authors:  Olga Epifano; Jurrien Dean
Journal:  Trends Endocrinol Metab       Date:  2002 May-Jun       Impact factor: 12.015

8.  Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression.

Authors:  Atsusi Hirata; Yukio Murakami; Masao Shoji; Yoshinori Kadoma; Seiichiro Fujisawa
Journal:  Anticancer Res       Date:  2005 Sep-Oct       Impact factor: 2.480

9.  Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships.

Authors:  Kelly E. Heim; Anthony R. Tagliaferro; Dennis J. Bobilya
Journal:  J Nutr Biochem       Date:  2002-10       Impact factor: 6.048

10.  The preventive effect of captopril or enalapril on reperfusion injury of the kidney of rats is independent of angiotensin II AT1 receptors.

Authors:  Hamid Reza Pazoki-Toroudi; Ali Hesami; Simin Vahidi; Farhad Sahebjam; Behjat Seifi; Bijan Djahanguiri
Journal:  Fundam Clin Pharmacol       Date:  2003-10       Impact factor: 2.748
View more
  3 in total

Review 1.  Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements.

Authors:  Vaishali Aggarwal; Hardeep S Tuli; Falak Thakral; Paavan Singhal; Diwakar Aggarwal; Saumya Srivastava; Anjana Pandey; Katrin Sak; Mehmet Varol; Md Asaduzzaman Khan; Gautam Sethi
Journal:  Exp Biol Med (Maywood)       Date:  2020-02-12

2.  Growth performance, morphometric of the small intestine, lymphoid organ, and ovary of laying hens supplemented with Dates (Phoenix dactylifera L.) extract in drinking water.

Authors:  L U Albab; T I Claudya; R Oktafianti; N Salsabila; R D Putri; H T S S G Saragih
Journal:  Vet World       Date:  2022-02-16

3.  Rhamnocitrin decreases fibrosis of ovarian granulosa cells by regulating the activation of the PPARγ/NF-κB/TGF-β1/Smad2/3 signaling pathway mediated by Wisp2.

Authors:  Yan-Yuan Zhou; Chun-Hua He; Huan Lan; Zhe-Wen Dong; Ya-Qi Wu; Jia-Le Song
Journal:  Ann Transl Med       Date:  2022-07
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.