Literature DB >> 30780130

WOMEN IN REPRODUCTIVE SCIENCE: Discovering science and the ovary: a career of joy.

JoAnne S Richards1.   

Abstract

My career has been about discovering science and learning the joys of the discovery process itself. It has been a challenging but rewarding process filled with many exciting moments and wonderful colleagues and students. Although I went to college to become a French major, I ultimately stumbled into research while pursuing a Masters Degree in teaching. Thus, my research career began in graduate school where I was studying NAD kinase in the ovary as a possible regulator of steroidogenesis, a big issue in the late 1960s. After a short excursion of teaching in North Dakota, I became a postdoctoral fellow at the University of Michigan, where radio-immuno assays and radio receptor assays had just come on the scene and were transforming endocrinology from laborious bioassays to quantitative science and of course these assays related to the ovary. From there I went to Baylor College of Medicine, a mecca of molecular biology, cloning genes and generating mouse models. It has been a fascinating and joyous journey.

Entities:  

Year:  2019        PMID: 30780130      PMCID: PMC6675678          DOI: 10.1530/REP-18-0513

Source DB:  PubMed          Journal:  Reproduction        ISSN: 1470-1626            Impact factor:   3.906


  69 in total

Review 1.  The ovary: basic biology and clinical implications.

Authors:  Joanne S Richards; Stephanie A Pangas
Journal:  J Clin Invest       Date:  2010-04-01       Impact factor: 14.808

2.  Mice null for Frizzled4 (Fzd4-/-) are infertile and exhibit impaired corpora lutea formation and function.

Authors:  Minnie Hsieh; Derek Boerboom; Masayuki Shimada; Yuet Lo; Albert F Parlow; Ulrich F O Luhmann; Wolfgang Berger; JoAnne S Richards
Journal:  Biol Reprod       Date:  2005-08-10       Impact factor: 4.285

Review 3.  Ovulation: new factors that prepare the oocyte for fertilization.

Authors:  Joanne S Richards
Journal:  Mol Cell Endocrinol       Date:  2005-04-29       Impact factor: 4.102

4.  Functional and subcellular changes in the A-kinase-signaling pathway: relation to aromatase and Sgk expression during the transition of granulosa cells to luteal cells.

Authors:  I J Gonzalez-Robayna; T N Alliston; P Buse; G L Firestone; J S Richards
Journal:  Mol Endocrinol       Date:  1999-08

5.  CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes.

Authors:  Heng-Yu Fan; Zhilin Liu; Peter F Johnson; JoAnne S Richards
Journal:  Mol Endocrinol       Date:  2010-12-22

6.  Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development.

Authors:  Derek Boerboom; Marilene Paquet; Minnie Hsieh; Jinsong Liu; Soazik P Jamin; Richard R Behringer; Jean Sirois; Makoto M Taketo; Joanne S Richards
Journal:  Cancer Res       Date:  2005-10-15       Impact factor: 12.701

7.  Transient expression of progesterone receptor messenger RNA in ovarian granulosa cells after the preovulatory luteinizing hormone surge.

Authors:  O K Park; K E Mayo
Journal:  Mol Endocrinol       Date:  1991-07

8.  Immune-like mechanisms in ovulation.

Authors:  JoAnne S Richards; Zhilin Liu; Masayuki Shimada
Journal:  Trends Endocrinol Metab       Date:  2008-04-11       Impact factor: 12.015

9.  Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation.

Authors:  Heng-Yu Fan; Masayuki Shimada; Zhilin Liu; Nicola Cahill; Noritaka Noma; Yun Wu; Jan Gossen; JoAnne S Richards
Journal:  Development       Date:  2008-06       Impact factor: 6.868

10.  Enhanced Inflammatory Transcriptome in the Granulosa Cells of Women With Polycystic Ovarian Syndrome.

Authors:  Jaye Adams; Zhilin Liu; Yi Athena Ren; Wan-Song Wun; Wei Zhou; Shlomit Kenigsberg; Clifford Librach; Cecilia Valdes; William Gibbons; JoAnne Richards
Journal:  J Clin Endocrinol Metab       Date:  2016-05-26       Impact factor: 5.958

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