Gabriela Corina Zaharie1, Monica Hasmasanu2, Ligia Blaga3, Melinda Matyas4, Daniel Muresan5, Sorana Daniela Bolboaca6. 1. Neonatology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. gabrielazaharie1966@gmail.com. 2. Neonatology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. monica.hasmasanu@gmail.com. 3. Neonatology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. blagaligia@yahoo.com. 4. Neonatology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. melimatyas@yahoo.com. 5. Obstetrics and Gynecology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. muresandaniel01@yahoo.com. 6. Medical Informatics and Biostatistics, department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy. sbolboaca@gmail.com.
Abstract
AIM: To asses the cardiac morphology and functional changes specific for newborns from intrauterine growth restriction (IUGR) pregnancies. MATERIAL AND METHOD: A cohort of IUGR infants were evaluated by serial echocardiographies at delivery and at the first and six months follow-ups. IUGR newborn delivery status was compared to that of newborns in the control group according to gestational age (AGA). RESULTS: Left heart measurements were significantly lower in IUGR newborns compared to AGA babies. Left ventricular size increased at follow-up inthe IUGR group (p<0.05). Systolic dysfunction (the myocardial performance index (MPI)> 0.47) was identified in 40% of the neonates in the IUGR group (16/40), respectively 4.76% in the control group. IUGR neonates had a significantly increased proportion of systolic malfunction (p=0.004). CONCLUSION: IUGR patients had reduced left ventricle dimensions compared to AGA babies. The MPI stands out as a marker of leftheart function in newborns. Systolic dysfunction was a hallmark of the cardiac adaptation in IUGR neonates.
AIM: To asses the cardiac morphology and functional changes specific for newborns from intrauterine growth restriction (IUGR) pregnancies. MATERIAL AND METHOD: A cohort of IUGR infants were evaluated by serial echocardiographies at delivery and at the first and six months follow-ups. IUGR newborn delivery status was compared to that of newborns in the control group according to gestational age (AGA). RESULTS: Left heart measurements were significantly lower in IUGR newborns compared to AGA babies. Left ventricular size increased at follow-up inthe IUGR group (p<0.05). Systolic dysfunction (the myocardial performance index (MPI)> 0.47) was identified in 40% of the neonates in the IUGR group (16/40), respectively 4.76% in the control group. IUGR neonates had a significantly increased proportion of systolic malfunction (p=0.004). CONCLUSION: IUGR patients had reduced left ventricle dimensions compared to AGA babies. The MPI stands out as a marker of leftheart function in newborns. Systolic dysfunction was a hallmark of the cardiac adaptation in IUGR neonates.