Literature DB >> 30776902

Sensitization in Heart Transplantation: Emerging Knowledge: A Scientific Statement From the American Heart Association.

Monica M Colvin, Jennifer L Cook, Patricia P Chang, Daphne T Hsu, Michael S Kiernan, Jon A Kobashigawa, JoAnn Lindenfeld, S Carolina Masri, Dylan V Miller, E Rene Rodriguez, Dolly B Tyan, Adriana Zeevi.   

Abstract

Sensitization, defined as the presence of circulating antibodies, presents challenges for heart transplant recipients and physicians. When present, sensitization can limit a transplantation candidate's access to organs, prolong wait time, and, in some cases, exclude the candidate from heart transplantation altogether. The management of sensitization is not yet standardized, and current therapies have not yielded consistent results. Although current strategies involve antibody suppression and removal with intravenous immunoglobulin, plasmapheresis, and antibody therapy, newer strategies with more specific targets are being investigated.

Keywords:  AHA Scientific Statements; antibodies; heart transplantation; human leukocyte antigen

Year:  2019        PMID： 30776902     DOI： 10.1161/CIR.0000000000000598

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


  9 in total

Review 1.  Management of the sensitized pediatric heart transplant patient.

Authors:  Erik L Frandsen; Erin L Albers
Journal:  Transl Pediatr       Date:  2019-10

2.  Sternum-Sparing Left Ventricular Assist Device Insertion Reduces Perioperative Transfusions and Blood Loss: A Single-Centre Canadian Experience.

Authors:  Vishnu Vasanthan; Jana Rieger; Daniel D Holloway; Brian Clarke; Robert Miller; William D T Kent
Journal:  CJC Open       Date:  2022-06-09

Review 3.  Heart Transplant Immunosuppression Strategies at Cedars-Sinai Medical Center.

Authors:  David H Chang; Jong-Chan Youn; Deanna Dilibero; Jignesh K Patel; Jon A Kobashigawa
Journal:  Int J Heart Fail       Date:  2020-09-29

4.  The Assessment and Outcomes of Crossmatching in Lung Transplantation in Korean Patients.

Authors:  Ha Eun Kim; Young Ho Yang; Hyo Chae Paik; Su Jin Jeong; Song Yee Kim; Moo Suk Park; Jin Gu Lee
Journal:  J Korean Med Sci       Date:  2022-06-06       Impact factor: 5.354

5.  Donor specific anti-HLA antibodies and cardiac allograft vasculopathy: A prospective study using highly automated 3-D optical coherence tomography analysis.

Authors:  Michal Pazdernik; Helena Bedanova; Zhi Chen; Josef Kautzner; Vojtech Melenovsky; Ivan Malek; Antonij Slavcev; Michaela Bartonova; Vladimir Karmazin; Tomas Eckhardt; Ales Tomasek; Eva Ozabalova; Tomas Kovarnik; Peter Wohlfahrt; Milan Sonka
Journal:  Transpl Immunol       Date:  2020-10-15       Impact factor: 2.032

6.  Successful Desensitization by Post-Centrifugal Plasma Filtration in Two Highly Sensitized Heart and Lung Transplant Recipients.

Authors:  Hyun-Ji Lee; Kyung-Hwa Shin; Hyung-Hoi Kim; Hyung Gon Je; Dohyung Kim; Woo Hyun Cho; Jeong Su Kim; Soo Yong Lee; Hye Ju Yeo
Journal:  Ann Lab Med       Date:  2020-09       Impact factor: 3.464

Review 7.  Current Desensitization Strategies in Heart Transplantation.

Authors:  Marlena V Habal
Journal:  Front Immunol       Date:  2021-08-24       Impact factor: 8.786

8.  Impact of Sex in the Efficacy of Perioperative Desensitization Procedures in Heart Transplantation: A Retrospective Cohort Study.

Authors:  Lee S Nguyen; Joe-Elie Salem; Marie-Cécile Bories; Guillaume Coutance; Julien Amour; Adrien Bougle; Caroline Suberbielle; Vissal-David Kheav; Maryvonnick Carmagnat; Philippe Rouvier; Matthias Kirsch; Shaida Varnous; Pascal Leprince; Samir Saheb
Journal:  Front Immunol       Date:  2021-07-07       Impact factor: 7.561

Review 9.  Rehabilitation in Pediatric Heart Failure and Heart Transplant.

Authors:  Ana Ubeda Tikkanen; Emily Berry; Erin LeCount; Katherine Engstler; Meredith Sager; Paul Esteso
Journal:  Front Pediatr       Date:  2021-05-19       Impact factor: 3.418
  9 in total

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