Literature DB >> 30776003

Cognitive Improvement with Glutathione Supplement in Alzheimer's Disease: A Way Forward.

Pravat K Mandal1,2, Deepika Shukla1, Manjari Tripathi3, Lars Ersland4,5,6.   

Abstract

Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting millions of people worldwide. The actual cause of AD is still unknown. Oxidative stress is believed to be important player in AD pathology. Glutathione (GSH) is a major antioxidant, and it is already known that GSH is depleted significantly in the hippocampal regions in mild cognitive impairment (MCI) and AD patients compared to healthy old subjects. Hence there is a serious discussion to improve the brain GSH level by supplementation. This editorial highlights the need for GSH supplementation for the cognitive enhancement in MCI and AD.

Entities:  

Year:  2019        PMID： 30776003     DOI： 10.3233/JAD-181054

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN： 1387-2877            Impact factor:   4.472


  14 in total

1.  Effects of 12 Weeks Cosmos caudatus Supplement among Older Adults with Mild Cognitive Impairment: A Randomized, Double-Blind and Placebo-Controlled Trial.

Authors:  Yee Xing You; Suzana Shahar; Nor Fadilah Rajab; Hasnah Haron; Hanis Mastura Yahya; Mazlyfarina Mohamad; Normah Che Din; Mohamad Yusof Maskat
Journal:  Nutrients       Date:  2021-01-29       Impact factor: 5.717

Review 2.  Alzheimer's disease treatment: The share of herbal medicines.

Authors:  Masoud Soheili; Mohammad Karimian; Gholamali Hamidi; Mahmoud Salami
Journal:  Iran J Basic Med Sci       Date:  2021-02       Impact factor: 2.699

Review 3.  Glutathione in Brain Disorders and Aging.

Authors:  Igor Y Iskusnykh; Anastasia A Zakharova; Dhruba Pathak
Journal:  Molecules       Date:  2022-01-05       Impact factor: 4.411

4.  α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats.

Authors:  Mateusz Maciejczyk; Ewa Żebrowska; Miłosz Nesterowicz; Małgorzata Żendzian-Piotrowska; Anna Zalewska
Journal:  Oxid Med Cell Longev       Date:  2022-03-29       Impact factor: 6.543

Review 5.  Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis.

Authors:  Germán Plascencia-Villa; George Perry
Journal:  Antioxid Redox Signal       Date:  2020-07-17       Impact factor: 8.401

6.  Quantitation of in vivo brain glutathione conformers in cingulate cortex among age-matched control, MCI, and AD patients using MEGA-PRESS.

Authors:  Deepika Shukla; Pravat Kumar Mandal; Manjari Tripathi; Gayatri Vishwakarma; Ritwick Mishra; Kanika Sandal
Journal:  Hum Brain Mapp       Date:  2019-10-04       Impact factor: 5.038

Review 7.  Nature's Derivative(s) as Alternative Anti-Alzheimer's Disease Treatments.

Authors:  Anuja Sharma; Yatender Kumar
Journal:  J Alzheimers Dis Rep       Date:  2019-11-21

8.  Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors.

Authors:  Priscilla Biswas; Cinzia Dellanoce; Alessandra Vezzoli; Simona Mrakic-Sposta; Mauro Malnati; Alberto Beretta; Roberto Accinni
Journal:  Nutrients       Date:  2020-10-22       Impact factor: 5.717

9.  A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data.

Authors:  Norah Alghamdi; Wennan Chang; Pengtao Dang; Xiaoyu Lu; Changlin Wan; Silpa Gampala; Zhi Huang; Jiashi Wang; Qin Ma; Yong Zang; Melissa Fishel; Sha Cao; Chi Zhang
Journal:  Genome Res       Date:  2021-07-22       Impact factor: 9.043

Review 10.  Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases.

Authors:  Pamela Maher; Antonio Currais; David Schubert
Journal:  Cell Chem Biol       Date:  2020-11-10       Impact factor: 8.116
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.