Brent Doney1, Laura Kurth1, Cara Halldin1, Janet Hale1, Steven M Frenk2. 1. Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia. 2. Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland.
Abstract
INTRODUCTION: This study examined the association of spirometry-defined airflow obstruction and self-reported COPD defined as self-reported doctor diagnosed chronic bronchitis or emphysema, with occupational exposure among ever-employed US adults. METHODS: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007-2008 to 2011-2012, a nationally representative study of the non-institutionalized civilian US population. Reported current and/or longest held job were used to create prevalence estimates and prevalence odds ratios (PORs) (adjusted for age, gender, race, and smoking status) for airflow obstruction and self-reported COPD by occupational exposure, determined using both NHANES participants' self-reported exposures and eight categories of COPD job exposure matrix (JEM) assigned exposures. RESULTS: Significant PORs for airflow obstruction and self-reported COPD respectively were observed with self-reported exposure for ≥20 years to mineral dust (POR = 1.44; 95% confidence interval (CI) 1.13-1.85; POR = 1.69; 95% CI 1.17-2.43) and exhaust fumes (POR = 1.65; 95% CI 1.27-2.15; POR = 2.22; 95% CI 1.37-3.58). Airflow obstruction or self-reported COPD were also associated with COPD-JEM assigned high exposure to mineral dust, combined dust, diesel exhaust, vapor-gas, sensitizers, and overall exposure. CONCLUSION: Airflow obstruction and self-reported COPD are associated with both self-reported and JEM-assigned exposures. Published 2019. This article is a U.S. Government work and is in the public domain in the USA.
INTRODUCTION: This study examined the association of spirometry-defined airflow obstruction and self-reported COPD defined as self-reported doctor diagnosed chronic bronchitis or emphysema, with occupational exposure among ever-employed US adults. METHODS: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007-2008 to 2011-2012, a nationally representative study of the non-institutionalized civilian US population. Reported current and/or longest held job were used to create prevalence estimates and prevalence odds ratios (PORs) (adjusted for age, gender, race, and smoking status) for airflow obstruction and self-reported COPD by occupational exposure, determined using both NHANES participants' self-reported exposures and eight categories of COPD job exposure matrix (JEM) assigned exposures. RESULTS: Significant PORs for airflow obstruction and self-reported COPD respectively were observed with self-reported exposure for ≥20 years to mineral dust (POR = 1.44; 95% confidence interval (CI) 1.13-1.85; POR = 1.69; 95% CI 1.17-2.43) and exhaust fumes (POR = 1.65; 95% CI 1.27-2.15; POR = 2.22; 95% CI 1.37-3.58). Airflow obstruction or self-reported COPD were also associated with COPD-JEM assigned high exposure to mineral dust, combined dust, diesel exhaust, vapor-gas, sensitizers, and overall exposure. CONCLUSION:Airflow obstruction and self-reported COPD are associated with both self-reported and JEM-assigned exposures. Published 2019. This article is a U.S. Government work and is in the public domain in the USA.
Authors: Paul D Blanc; Mark D Eisner; John R Balmes; Laura Trupin; Edward H Yelin; Patricia P Katz Journal: Am J Ind Med Date: 2005-08 Impact factor: 2.214
Authors: Brent Doney; Eva Hnizdo; Monica Graziani; Greg Kullman; Cecil Burchfiel; Sherry Baron; Kaori Fujishiro; Paul Enright; John L Hankinson; Karen Hinckley Stukovsky; Christopher J Martin; Kathleen M Donohue; R Graham Barr Journal: COPD Date: 2014-02-25 Impact factor: 2.409
Authors: Debra T Silverman; Claudine M Samanic; Jay H Lubin; Aaron E Blair; Patricia A Stewart; Roel Vermeulen; Joseph B Coble; Nathaniel Rothman; Patricia L Schleiff; William D Travis; Regina G Ziegler; Sholom Wacholder; Michael D Attfield Journal: J Natl Cancer Inst Date: 2012-03-05 Impact factor: 13.506
Authors: Brent C Doney; Paul K Henneberger; Michael J Humann; Xiaoming Liang; Kevin M Kelly; Jean M Cox-Ganser Journal: MMWR Surveill Summ Date: 2017-11-03
Authors: George L Delclos; David Gimeno; Ahmed A Arif; Fernando G Benavides; Jan-Paul Zock Journal: Am J Epidemiol Date: 2009-01-06 Impact factor: 4.897