Literature DB >> 30775785

Synchronous hepatectomy and splenectomy vs hepatectomy for selected patients with hepatocellular carcinoma and clinically significant portal hypertension: A systematic review and meta-analysis.

Junjie Kong1, Shu Shen1, Wentao Wang1.   

Abstract

This review aimed to evaluate the safety, feasibility, and effectiveness of synchronous hepatectomy and splenectomy for selected patients with hepatocellular carcinoma and clinically significant portal hypertension compared to hepatectomy alone. A systematic search in electronic databases was conducted. A total of 8 studies including 1445 patients were reviewed. While perioperative safety was satisfactory, synchronous hepatectomy and splenectomy were associated with a significant improvement of 5-year overall survival (odds ratio = 1.81; 95% confidence interval: 1.35, 2.42; P < 0.0001).
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  clinically significant portal hypertension; hepatectomy; hepatocellular carcinoma; hypersplenism; splenectomy

Mesh：

Year:  2019        PMID： 30775785     DOI： 10.1002/jso.25392

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  7 in total

1.  Single-cell RNA Sequencing Analysis Reveals New Immune Disorder Complexities in Hypersplenism.

Authors:  Hai-Chao Zhao; Chang-Zhou Chen; Huang-Qin Song; Xiao-Xiao Wang; Lei Zhang; Hao-Liang Zhao; Jie-Feng He
Journal:  Front Immunol       Date:  2022-07-05       Impact factor: 8.786

2.  The Benefits of Radical Treatments with Synchronous Splenectomy for Patients with Hepatocellular Carcinoma and Portal Hypertension.

Authors:  Qikun Zhang; Qi Li; Fuchao Shang; Guangming Li; Menglong Wang
Journal:  Cancers (Basel)       Date:  2022-06-28       Impact factor: 6.575

3.  Does splenectomy significantly improve the prognosis of hepatocellular carcinoma patients with hypersplenism? A systematic review and meta-analysis.

Authors:  Xue-Bing Shi; Jin-Kai Feng; Jing-Han Wang; Xiao-Qing Jiang
Journal:  Ann Transl Med       Date:  2021-04

Review 4.  Platelets and Hepatocellular Cancer: Bridging the Bench to the Clinics.

Authors:  Quirino Lai; Alessandro Vitale; Tommaso M Manzia; Francesco G Foschi; Giovanni B Levi Sandri; Martina Gambato; Fabio Melandro; Francesco P Russo; Luca Miele; Luca Viganò; Patrizia Burra; Edoardo G Giannini
Journal:  Cancers (Basel)       Date:  2019-10-15       Impact factor: 6.639

5.  Splenectomy before hepatectomy for patients with hepatocellular carcinoma and hypersplenism: A retrospective study.

Authors:  Chenyang Zhou; Yueying Huang; Chang Shu; Jiangmin Zhou; Xinsheng Hu; Jinlin Wang; Yuwei Wang; Zhanguo Zhang; Lin Chen; Xiaoping Chen; Zhiwei Zhang
Journal:  Medicine (Baltimore)       Date:  2021-01-29       Impact factor: 1.817

6.  Impact of splenomegaly and splenectomy on prognosis in hepatocellular carcinoma with portal vein tumor thrombus treated with hepatectomy.

Authors:  Zong-Tao Chai; Xiu-Ping Zhang; Min Shao; Jian-Yang Ao; Zhen-Hua Chen; Fan Zhang; Yi-Ren Hu; Cheng-Qian Zhong; Jian-Hua Lin; Kun-Peng Fang; Meng-Chao Wu; Wan Yee Lau; Shu-Qun Cheng
Journal:  Ann Transl Med       Date:  2021-02

7.  Multimodal approach to portal hypertension and gastric varices before hepatic resection for hepatocellular carcinoma: a case report.

Authors:  Norifumi Harimoto; Kenichiro Araki; Ryo Muranushi; Kouki Hoshino; Kei Hagiwara; Norihiro Ishii; Mariko Tsukagoshi; Takamichi Igarashi; Akira Watanabe; Norio Kubo; Kei Shibuya; Masaya Miyazaki; Hirofumi Kawanaka; Ken Shirabe
Journal:  Surg Case Rep       Date:  2020-07-31
  7 in total

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