Literature DB >> 30774085

[France and Great-Britain at the age of genomic medicine: new ethical challenges in reproductive medicine].

Ruth Horn1.   

Abstract

The announcement of the French Plan 'France Médecine Génomique 2015' demonstrates the will of the public authorities to make genomic medicine one of the flagships of public health and scientific research. It is against this backdrop that France announced its cooperation with Great Britain, one of the global leaders in genomics. The cooperation at an international level requires a common normative framework that addresses the new ethical challenges presented by genomic medicine. In order for such a framework to be adapted to different national contexts, it is important to identify and analyse the emerging ethical questions in general as well as within their specific national contexts. This article discusses the international implications of genomic medicine, and more precisely, the rise of international competitiveness in France. In a next step, the article explores the ethical implications of genomic medicine by taking the prenatal context as a case study. Finally, the article reflects on the way national contexts impact on the emerging ethical questions in France, as compared to Great Britain.
© 2019 médecine/sciences – Inserm.

Entities:  

Mesh:

Year:  2019        PMID: 30774085      PMCID: PMC7115973          DOI: 10.1051/medsci/2019004

Source DB:  PubMed          Journal:  Med Sci (Paris)        ISSN: 0767-0974            Impact factor:   0.818


  25 in total

Review 1.  From prenatal genomic diagnosis to fetal personalized medicine: progress and challenges.

Authors:  Diana W Bianchi
Journal:  Nat Med       Date:  2012-07-06       Impact factor: 53.440

2.  [Sequencing babies?].

Authors:  Bertrand Jordan
Journal:  Med Sci (Paris)       Date:  2015-10-19       Impact factor: 0.818

3.  Exome sequencing for prenatal diagnosis of fetuses with sonographic abnormalities.

Authors:  Suzanne Drury; Hywel Williams; Natalie Trump; Christopher Boustred; Nicholas Lench; Richard H Scott; Lyn S Chitty
Journal:  Prenat Diagn       Date:  2015-09-11       Impact factor: 3.050

Review 4.  Noninvasive Prenatal DNA Testing: The Vanguard of Genomic Medicine.

Authors:  Lisa Hui; Diana W Bianchi
Journal:  Annu Rev Med       Date:  2016-10-10       Impact factor: 13.739

5.  Noninvasive prenatal testing for early sex identification: a few benefits and many concerns.

Authors:  Audrey R Chapman; Peter A Benn
Journal:  Perspect Biol Med       Date:  2013       Impact factor: 1.416

6.  Medical ethics in the 21st century.

Authors:  M Parker; T Hope
Journal:  J Intern Med       Date:  2000-07       Impact factor: 8.989

7.  Non-invasive prenatal testing for Down's syndrome: pregnant women's views and likely uptake.

Authors:  C Lewis; C Silcock; L S Chitty
Journal:  Public Health Genomics       Date:  2013-07-25       Impact factor: 2.000

8.  Explaining variation in Down's syndrome screening uptake: comparing the Netherlands with England and Denmark using documentary analysis and expert stakeholder interviews.

Authors:  Neeltje M T H Crombag; Ynke E Vellinga; Sandra A Kluijfhout; Louise D Bryant; Pat A Ward; Rita Iedema-Kuiper; Peter C J I Schielen; Jozien M Bensing; Gerard H A Visser; Ann Tabor; Janet Hirst
Journal:  BMC Health Serv Res       Date:  2014-09-25       Impact factor: 2.655

Review 9.  Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing.

Authors:  Ruth Horn; Michael Parker
Journal:  Prenat Diagn       Date:  2017-08-07       Impact factor: 3.050

10.  Women's Experiences and Preferences for Service Delivery of Non-Invasive Prenatal Testing for Aneuploidy in a Public Health Setting: A Mixed Methods Study.

Authors:  Celine Lewis; Melissa Hill; Lyn S Chitty
Journal:  PLoS One       Date:  2016-04-05       Impact factor: 3.240

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