Samir S Khariwala1,2, Nathan Rubin2,3, Irina Stepanov2,4, Nicole Nollen5, Jasjit S Ahluwalia6, Heather H Nelson2,7, Dorothy K Hatsukami2,8. 1. Department of Otolaryngology - Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota. 2. Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota. 3. Department of Biostatistics, University of Minnesota, Minneapolis, Minnesota. 4. Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota. 5. Department of Preventive Medicine and Public Health, University of Kansas, Kansas City, Kansas. 6. Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence. 7. Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota. 8. Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota.
Abstract
BACKGROUND: Tobacco cessation methods employed by patients with head and neck cancer (HNSCC) are previously unstudied and have the potential to inform choice of cessation method and necessary abstinence support. METHODS: A total of 130 current smokers with HNSCC were queried regarding prior unsuccessful tobacco cessation techniques, product used (cold turkey, varenicline, and nicotine patch/gum), and maximum time abstained from smoking. RESULTS: One hundred six smokers retrospectively reported using one of the four main quit methods. Unassisted cessation ("cold turkey") was the most commonly used method (P < .001). A multiple ordinal logistic general estimating equation analysis revealed that cold turkey had increased odds [5.2 (95% confidence interval [CI]: 2.2, 11.8) and 4.3 (95% CI: 1.5, 12.9)] of achieving a longer quit duration than the nicotine patch or varenicline, respectively. CONCLUSIONS: Among smokers developing HNSCC, previous cessation attempts were most commonly unassisted. This method was associated with longest abstinence periods. These data suggest insufficient support and education regarding behavioral and pharmacologic cessation therapies.
BACKGROUND:Tobacco cessation methods employed by patients with head and neck cancer (HNSCC) are previously unstudied and have the potential to inform choice of cessation method and necessary abstinence support. METHODS: A total of 130 current smokers with HNSCC were queried regarding prior unsuccessful tobacco cessation techniques, product used (cold turkey, varenicline, and nicotine patch/gum), and maximum time abstained from smoking. RESULTS: One hundred six smokers retrospectively reported using one of the four main quit methods. Unassisted cessation ("cold turkey") was the most commonly used method (P < .001). A multiple ordinal logistic general estimating equation analysis revealed that cold turkey had increased odds [5.2 (95% confidence interval [CI]: 2.2, 11.8) and 4.3 (95% CI: 1.5, 12.9)] of achieving a longer quit duration than the nicotine patch or varenicline, respectively. CONCLUSIONS: Among smokers developing HNSCC, previous cessation attempts were most commonly unassisted. This method was associated with longest abstinence periods. These data suggest insufficient support and education regarding behavioral and pharmacologic cessation therapies.
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