Sita Patel1, Daniel Rinchuse2, Thomas Zullo3, Rekha Wadhwa2. 1. Seton Hill University, Department of Orthodontics and Dentofacial Orthopedics, Greensburg, PA, USA. Electronic address: s.patel2@setonhill.edu. 2. Seton Hill University, Department of Orthodontics and Dentofacial Orthopedics, Greensburg, PA, USA. 3. Seton Hill University, Department of Biostatistics, Greensburg, PA, USA.
Abstract
OBJECTIVE: This systematic review aimed to clarify whether there are any significant long-term sequelae to wearing mandibular advancement devices focusing on dental and skeletal effects in adults with OSA. MATERIALS AND METHODS: Databases, including PubMed, Medline, Embase, Web of Science, Cochrane Central Register of Controlled Trials, and SAGE Journals. Hand searches and grey literature were also used. A piloted data collection form was used to extract the appropriate data. RESULTS: Twenty-three reports of 19 studies were included. Five had serious risk of bias while 18 had moderate risk of bias. Meta-analysis revealed a significant change in overbite and overjet. I-squared analysis showed a high level of statistical heterogeneity. A moderate correlation was found between wear time and amount of change. CONCLUSION: Mandibular advancement devices will cause a small but statistically significant change in the dentition of long-term wearers. Skeletal changes are generally secondary to dental changes.
OBJECTIVE: This systematic review aimed to clarify whether there are any significant long-term sequelae to wearing mandibular advancement devices focusing on dental and skeletal effects in adults with OSA. MATERIALS AND METHODS: Databases, including PubMed, Medline, Embase, Web of Science, Cochrane Central Register of Controlled Trials, and SAGE Journals. Hand searches and grey literature were also used. A piloted data collection form was used to extract the appropriate data. RESULTS: Twenty-three reports of 19 studies were included. Five had serious risk of bias while 18 had moderate risk of bias. Meta-analysis revealed a significant change in overbite and overjet. I-squared analysis showed a high level of statistical heterogeneity. A moderate correlation was found between wear time and amount of change. CONCLUSION: Mandibular advancement devices will cause a small but statistically significant change in the dentition of long-term wearers. Skeletal changes are generally secondary to dental changes.
Authors: Carmen Karadeniz; Ken Wei Chen Lee; Daniel Lindsay; Ersan I Karadeniz; Carlos Flores-Mir Journal: Angle Orthod Date: 2022-03-01 Impact factor: 2.079