Literature DB >> 30769249

Antibiotics for Groin Hernia Repair According to Evidence-Based Guidelines: Time for Action in Ghana.

Adam Gyedu1, Micah Katz2, Kwabena Agbedinu3, Peter Donkor4, Charles Mock5.   

Abstract

BACKGROUD: Groin hernia repairs (GHR), though classified as clean surgeries, are associated with varying rates of surgical site infections. We assessed the practices of surgeons in Ghana regarding antibiotic use for GHR in comparison to evidence-based international guidelines (EBIG).
METHODS: We interviewed surgeons trained by the Ghana College of Physicians and Surgeons (GCPS), from inception (2003) through 2016, about their use of antibiotics for GHR. We defined the outcome variable of consistently following EBIG in antibiotics use for GHR. Logistic regression was used to examine how a priori selected covariates contributed to the outcome.
RESULTS: Eighty-two of 117 surgeons reported performing/supervising at least one GHR per week. They performed/supervised a mean of five GHR per week. Thirty-two (40%) reported using mesh for at least 50% of GHR. For primary GHR, 75% of surgeons administered antibiotics according to EBIG, whereas for GHR with mesh only, 45% did so. Predictors of consistently following EBIG were increasing number of GHR performed per week (adjusted odds ratio 1.44, 95% CI 1.07-1.96) and increasing time spent for clinical work (adjusted odds ratio 0.95, 95% CI 0.91-0.99). Years of practice since GCPS graduation, total operations performed per week, and hospital level of practice were not predictive of the outcome variable.
CONCLUSIONS: Two-thirds of Ghanaian surgeons interviewed do not consistently administer antibiotics for GHR per EBIG, raising the need to improve access to evidence-based medical information overall to guide practice. Determining local surgical site infections rates to guide antibiotic use in GHR will be useful in Ghana and other LMICs.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antibiotics; Ghana; Groin hernia repair; Low- and middle-income country

Mesh:

Substances:

Year:  2019        PMID: 30769249      PMCID: PMC6451880          DOI: 10.1016/j.jss.2019.01.040

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  24 in total

1.  Predictive risk score for infection after inguinal hernia repair.

Authors:  Patrick Pessaux; Emilie Lermite; Eric Blezel; Simon Msika; Jean-Marie Hay; Yves Flamant; Varma Deepak; Jean-Pierre Arnaud
Journal:  Am J Surg       Date:  2006-08       Impact factor: 2.565

2.  Clinical practice guidelines for antimicrobial prophylaxis in surgery.

Authors:  Dale W Bratzler; E Patchen Dellinger; Keith M Olsen; Trish M Perl; Paul G Auwaerter; Maureen K Bolon; Douglas N Fish; Lena M Napolitano; Robert G Sawyer; Douglas Slain; James P Steinberg; Robert A Weinstein
Journal:  Am J Health Syst Pharm       Date:  2013-02-01       Impact factor: 2.637

3.  Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial.

Authors:  M A Yerdel; E B Akin; S Dolalan; A G Turkcapar; M Pehlivan; I E Gecim; E Kuterdem
Journal:  Ann Surg       Date:  2001-01       Impact factor: 12.969

Review 4.  Antibiotic prophylaxis for hernia repair.

Authors:  Francisco Javier Sanchez-Manuel; Javier Lozano-García; Juan Luis Seco-Gil
Journal:  Cochrane Database Syst Rev       Date:  2012-02-15

5.  Characterizing the global burden of surgical disease: a method to estimate inguinal hernia epidemiology in Ghana.

Authors:  Jessica H Beard; Lawrence B Oresanya; Michael Ohene-Yeboah; Rochelle A Dicker; Hobart W Harris
Journal:  World J Surg       Date:  2013-03       Impact factor: 3.352

6.  Community surveillance of complications after hernia surgery.

Authors:  I S Bailey; S E Karran; K Toyn; P Brough; C Ranaboldo; S J Karran
Journal:  BMJ       Date:  1992-02-22

7.  Essential surgery at the district hospital: a retrospective descriptive analysis in three African countries.

Authors:  Moses Galukande; Johan von Schreeb; Andreas Wladis; Naboth Mbembati; Helder de Miranda; Margaret E Kruk; Sam Luboga; Alphonsus Matovu; Colin McCord; S Khady Ndao-Brumblay; Doruk Ozgediz; Peter C Rockers; Ana Romàn Quiñones; Fernando Vaz; Haile T Debas; Sarah B Macfarlane
Journal:  PLoS Med       Date:  2010-03-09       Impact factor: 11.069

8.  European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.

Authors:  M P Simons; T Aufenacker; M Bay-Nielsen; J L Bouillot; G Campanelli; J Conze; D de Lange; R Fortelny; T Heikkinen; A Kingsnorth; J Kukleta; S Morales-Conde; P Nordin; V Schumpelick; S Smedberg; M Smietanski; G Weber; M Miserez
Journal:  Hernia       Date:  2009-07-28       Impact factor: 4.739

9.  International guidelines for groin hernia management.

Authors: 
Journal:  Hernia       Date:  2018-01-12       Impact factor: 4.739

10.  Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study.

Authors: 
Journal:  Lancet Infect Dis       Date:  2018-02-13       Impact factor: 25.071

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  1 in total

Review 1.  Supporting global antimicrobial stewardship: antibiotic prophylaxis for the prevention of surgical site infection in low- and middle-income countries (LMICs): a scoping review and meta-analysis.

Authors:  Lesley Cooper; Jacqueline Sneddon; Daniel Kwame Afriyie; Israel A Sefah; Amanj Kurdi; Brian Godman; R Andrew Seaton
Journal:  JAC Antimicrob Resist       Date:  2020-10-05
  1 in total

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