Literature DB >> 30767810

Susceptibility of Candida auris and Candida albicans to 21 germicides used in healthcare facilities.

William A Rutala1, Hajime Kanamori1, Maria F Gergen2, Emily E Sickbert-Bennett1, David J Weber1.   

Abstract

Candida auris is an emerging fungal pathogen that is often resistant to major classes of antifungal drugs. It is considered a serious global health threat because it can cause severe infections with frequent mortality in more than a dozen countries. It can survive on healthcare environmental surfaces for at least 7 days and can cause outbreaks in healthcare facilities. Clearly, infection prevention strategies, such as surface disinfection, will be essential to controlling Candida transmission. Unfortunately, data on the activity of antiseptics and disinfectants used in healthcare to inactivate this pathogen are limited.1-5 In this study, we investigated 12 different disinfectants (ie, 8 low- and intermediate-level disinfectants in 2 dilutions of sodium hypochlorite and 5 high-level disinfectants/chemical sterilants) and 9 antiseptics commonly used in healthcare facilities for their antimicrobial activity against C. auris and C. albicans.

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Year:  2019        PMID: 30767810     DOI: 10.1017/ice.2019.1

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  18 in total

1.  Transcriptional Response of Candida auris to the Mrr1 Inducers Methylglyoxal and Benomyl.

Authors:  Amy R Biermann; Deborah A Hogan
Journal:  mSphere       Date:  2022-04-27       Impact factor: 5.029

2.  Reverse Transcription-Quantitative Real-Time PCR (RT-qPCR) Assay for the Rapid Enumeration of Live Candida auris Cells from the Health Care Environment.

Authors:  Bryanna Lexus Freitas; Lynn Leach; Vishnu Chaturvedi; Sudha Chaturvedi
Journal:  J Clin Microbiol       Date:  2021-12-08       Impact factor: 11.677

3.  Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2.

Authors:  Jennifer L Cadnum; Daniel F Li; Lucas D Jones; Sarah N Redmond; Basya Pearlmutter; Brigid M Wilson; Curtis J Donskey
Journal:  Pathog Immun       Date:  2020-05-22

4.  Effectiveness of Ultraviolet-C Light and a High-Level Disinfection Cabinet for Decontamination of N95 Respirators.

Authors:  Jennifer L Cadnum; Daniel F Li; Sarah N Redmond; Amrita R John; Basya Pearlmutter; Curtis J Donskey
Journal:  Pathog Immun       Date:  2020-04-20

Review 5.  New and emerging infectious diseases (Ebola, Middle Eastern respiratory syndrome coronavirus, carbapenem-resistant Enterobacteriaceae, Candida auris): Focus on environmental survival and germicide susceptibility.

Authors:  David J Weber; Emily E Sickbert-Bennett; Hajime Kanamori; William A Rutala
Journal:  Am J Infect Control       Date:  2019-06       Impact factor: 2.918

Review 6.  Review on Antifungal Resistance Mechanisms in the Emerging Pathogen Candida auris.

Authors:  Farid Chaabane; Artan Graf; Léonard Jequier; Alix T Coste
Journal:  Front Microbiol       Date:  2019-11-29       Impact factor: 5.640

7.  Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies.

Authors:  Xin Huang; Charlotte Hurabielle; Rebecca A Drummond; Nicolas Bouladoux; Jigar V Desai; Choon K Sim; Yasmine Belkaid; Michail S Lionakis; Julia A Segre
Journal:  Cell Host Microbe       Date:  2020-12-31       Impact factor: 21.023

8.  Effectiveness of germicidal ultraviolet light to inactivate coronaviruses on personal protective equipment to reduce nosocomial transmission.

Authors:  Carolina Camargo; Andréanne Lupien; Fiona McIntosh; Dick Menzies; Marcel A Behr; Selena M Sagan
Journal:  Infect Control Hosp Epidemiol       Date:  2021-06-21       Impact factor: 6.520

Review 9.  Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings.

Authors:  Diego H Caceres; Kaitlin Forsberg; Rory M Welsh; David Joseph Sexton; Shawn R Lockhart; Brendan R Jackson; Tom Chiller
Journal:  J Fungi (Basel)       Date:  2019-11-28

10.  Repositionable Compounds with Antifungal Activity against Multidrug Resistant Candida auris Identified in the Medicines for Malaria Venture's Pathogen Box.

Authors:  Gina Wall; Natalia Herrera; José L Lopez-Ribot
Journal:  J Fungi (Basel)       Date:  2019-10-01
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