Literature DB >> 30767631

Metabolomic diagnostics and human digital image.

Elena E Balashova1, Petr G Lokhov1, Elena A Ponomarenko1,2, Sergey S Markin1, Andrey V Lisitsa1, Alexander I Archakov1.   

Abstract

The existing clinical laboratory practice has limitations in terms of specificity and sensitivity of diagnosis, making the introduction of new methods in medicine more topical. Application of 'omics' technologies, especially metabolomics, allows overcoming these limitations. The composition of blood metabolites reflects the physical state of an organism at the molecular level. The analysis of blood metabolome can serve as effective means of diagnosis, implementation of which in healthcare is timely and relevant. This paper demonstrates the versatility of metabolomic diagnostics, its applicability to various diseases. We discussed the standard of human digital image, which includes the metabolomic data sufficient to make an accurate assessment of general health and carry out precision diagnostics of a wide range of diseases.

Entities:  

Keywords:  blood; direct mass spectrometry; human digital image; laboratory-based diagnostics; metabolomics; precision medicine

Mesh:

Year:  2019        PMID: 30767631     DOI: 10.2217/pme-2018-0066

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  3 in total

Review 1.  Metabolomics Community in Russia: History of Development, Key Participants, and Results.

Authors:  Elena E Balashova; Dmitry L Maslov; Oxana P Trifonova
Journal:  BioTech (Basel)       Date:  2020-10-25

2.  An Open-Source Pipeline for Processing Direct Infusion Mass Spectrometry Data of the Human Plasma Metabolome.

Authors:  Anna Kozlova; Timur Shkrigunov; Semyon Gusev; Maria Guseva; Elena Ponomarenko; Andrey Lisitsa
Journal:  Metabolites       Date:  2022-08-21

Review 3.  Defining Blood Plasma and Serum Metabolome by GC-MS.

Authors:  Olga Kiseleva; Ilya Kurbatov; Ekaterina Ilgisonis; Ekaterina Poverennaya
Journal:  Metabolites       Date:  2021-12-24
  3 in total

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