Literature DB >> 30763116

Long-term Outcomes of Meniscal Allograft Transplantation With and Without Extrusion: Mean 12.3-Year Follow-up Study.

Sang-Min Lee1, Seong-Il Bin1, Jong-Min Kim1, Bum-Sik Lee1, Chang-Rack Lee2, Dong-Wook Son3, Jun-Gu Park1.   

Abstract

BACKGROUND: Meniscal allograft transplantation (MAT) is a widely performed surgical technique used to reconstruct meniscal deficiencies after meniscectomy. However, the long-term effects of extrusion on clinical and radiologic outcomes are unclear. HYPOTHESIS: In long-term follow-up, extrusion after MAT would show poorer outcomes than nonextrusion and would lead to faster progression of arthritic changes. STUDY
DESIGN: Cohort study; Level of evidence, 3.
METHODS: Forty-five MAT cases (lateral, n = 36; medial meniscal, n = 9) with a minimum 8-year follow-up period were selected. The mean follow-up period was 12.3 years (range, 8.0-19.6 years). Data were collected on patients' sex, age, surgical side, and mechanical axis deviation. Patients were categorized into 2 groups: extrusion (≥3 mm) and nonextrusion (<3 mm). Categories were based on extrusion length measured via magnetic resonance imaging taken 1 year after surgery. Joint space width (JSW) on the affected and contralateral sides was measured on bilateral weightbearing posterior-anterior radiographs at 45° of flexion at 3 time points (preoperative, 4-6 years postoperative, and >8 years postoperative). Differences of the measured and relative JSW values between the groups and differences at different time points were analyzed. The Lysholm score was used to evaluate clinical function.
RESULTS: Mean ± SD extrusion was 3.07 ± 0.82 mm. The extrusion and nonextrusion groups were composed of 19 (42.2%) and 26 (57.8%) patients, respectively. Analysis of JSW showed a difference in relative JSW between the groups at >8 years ( P = .017). At the point of transition from 4 to 6 years to >8 years, the differences in absolute JSW values were -1.25 ± 0.78 mm (extrusion group) and -0.58 ± 0.66 mm (nonextrusion group; P < .001). Relative JSW values also differed between groups (extrusion group, -0.22 ± 0.13; nonextrusion group, -0.04 ± 0.18; P < .001). No differences were observed in the Lysholm scores between the groups at each time point.
CONCLUSION: Long-term follow-up after MAT revealed a greater decrease in JSW in the extrusion group than in the nonextrusion group. However, no significant differences in clinical outcomes were observed.

Entities:  

Keywords:  extrusion; joint space width; meniscal allograft transplantation; meniscus

Mesh:

Year:  2019        PMID: 30763116     DOI: 10.1177/0363546518825251

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  9 in total

Review 1.  Surgical and tissue engineering strategies for articular cartilage and meniscus repair.

Authors:  Heenam Kwon; Wendy E Brown; Cassandra A Lee; Dean Wang; Nikolaos Paschos; Jerry C Hu; Kyriacos A Athanasiou
Journal:  Nat Rev Rheumatol       Date:  2019-07-11       Impact factor: 20.543

2.  Biomechanical Comparison of Meniscal Allograft Root Fixation Techniques: Anterograde Interference Bone Plug Fixation Yields Favorable Results Compared to Transosseous Suture Fixation Alone.

Authors:  Andrzej Brzezinski; Casey Imbergamo; William Pfaff; Rae Tarapore; Matthew Nasra; Michael Simon; Charles Gatt
Journal:  Arthrosc Sports Med Rehabil       Date:  2022-02-11

Review 3.  Clinical significance and management of meniscal extrusion in different knee pathologies: a comprehensive review of the literature and treatment algorithm.

Authors:  Konstantinos G Makiev; Ioannis S Vasios; Paraskevas Georgoulas; Konstantinos Tilkeridis; Georgios Drosos; Athanasios Ververidis
Journal:  Knee Surg Relat Res       Date:  2022-07-18

4.  Increased MRI Signal Intensity of Allografts in the Midterm Period After Meniscal Allograft Transplant: An Evaluation of Clinical Significance According to Location and Morphology.

Authors:  Jun-Gu Park; Seong-Il Bin; Jong-Min Kim; Bum-Sik Lee; Sang-Min Lee; Ju-Ho Song
Journal:  Orthop J Sports Med       Date:  2021-08-26

5.  Lateral Capsular Stabilization in Lateral Meniscal Allograft Transplantation.

Authors:  Young-Jin Seo; Nam-Hong Choi; Byung-Hun Hwangbo; Ji-Sun Hwang; Brian N Victoroff
Journal:  Orthop J Sports Med       Date:  2021-11-01

6.  Correlation Between Anatomic Landmarks and Bony Trough Position in Lateral Meniscal Allograft Transplant.

Authors:  Nam-Hong Choi; Bong-Seok Yang; Dong-Min Lee; Jong-Seok Lee; Brian N Victoroff
Journal:  Orthop J Sports Med       Date:  2022-08-24

7.  Effect of Preoperative Joint Space Width on Lateral Meniscal Allograft Transplantation: Outcomes at Midterm Follow-up.

Authors:  Dhong Won Lee; Dong Ryun Lee; Min Ah Kim; Joon Kyu Lee; Jin Goo Kim
Journal:  Orthop J Sports Med       Date:  2022-09-01

8.  Three-dimensional meniscus allograft sizing-a study of 280 healthy menisci.

Authors:  Silvan Beeler; Lukas Jud; Marco von Atzigen; Reto Sutter; Philipp Fürnstahl; Sandro F Fucentese; Lazaros Vlachopoulos
Journal:  J Orthop Surg Res       Date:  2020-02-24       Impact factor: 2.359

9.  Progression of Allograft Extrusion in Both the Coronal and Sagittal Planes at Midterm Follow-up After Medial Meniscal Allograft Transplant.

Authors:  Hanwook Kim; Seong-Il Bin; Jong-Min Kim; Bum-Sik Lee; Dong-Wook Sohn
Journal:  Orthop J Sports Med       Date:  2021-02-09
  9 in total

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