| Literature DB >> 30762361 |
Qihao Wu1,2, Fei Ye2, Xiao-Lu Li3, Lin-Fu Liang4, Jiadong Sun5, Han Sun3, Yue-Wei Guo1,2, Hong Wang1.
Abstract
A detailed chemical investigation of the Chinese soft coral Lemnalia flava yielded four new nardosinane-type sesquiterpenoids (1-4), one new neolemnane-type sesquiterpenoid (5), and one new sesquiterpenoid with an uncommon 6/9 fused bicyclic skeleton (6), together with two known related compounds (7 and 8). The structures and absolute configurations of 1-8 were determined on the basis of extensive spectroscopic data analyses, X-ray diffraction analysis, chemical reactions, and computer-assisted structural elucidation including 13C NMR data calculation, residual dipolar coupling based NMR analysis, and time-dependent density functional theoryelectronic circular dichroism calculation. Plausible biogenetic pathways of two uncommon sesquiterpenoids (4 and 6) were proposed.Entities:
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Year: 2019 PMID： 30762361 DOI： 10.1021/acs.joc.8b02912
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354