Literature DB >> 30759379

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons.

Eric Deneault, Sean H White, Deivid C Rodrigues, P Joel Ross, Muhammad Faheem, Kirill Zaslavsky, Zhuozhi Wang, Roumiana Alexandrova, Giovanna Pellecchia, Wei Wei, Alina Piekna, Gaganjot Kaur, Jennifer L Howe, Vickie Kwan, Bhooma Thiruvahindrapuram, Susan Walker, Anath C Lionel, Peter Pasceri, Daniele Merico, Ryan K C Yuen, Karun K Singh, James Ellis, Stephen W Scherer.   

Abstract

Entities:  

Year:  2019        PMID: 30759379      PMCID: PMC6373432          DOI: 10.1016/j.stemcr.2019.01.008

Source DB:  PubMed          Journal:  Stem Cell Reports        ISSN: 2213-6711            Impact factor:   7.765


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(Stem Cell Reports 11, 1211–1225; January 13, 2018) The original representative trace of excitatory post-synaptic current (EPSC) for AFF2−/y was used twice by mistake to generate the ASTN2−/y cropped trace on the top panel of Figure 5A. However, we confirm that the original data was not a duplicate; only the image file was cropped incorrectly as a display figure for the trace. We have made a new Figure 5 with the correct ASTN2 trace cropped in Figure 5A. None of the original data or interpretation of the data was impacted. Electrophysiological Phenotyping of KO iPSC-Derived Neurons (corrected) Electrophysiological Phenotyping of KO iPSC-Derived Neurons (original)
  5 in total

Review 1.  Getting to the Cores of Autism.

Authors:  Lilia M Iakoucheva; Alysson R Muotri; Jonathan Sebat
Journal:  Cell       Date:  2019-09-05       Impact factor: 41.582

2.  8p23.2-pter Microdeletions: Seven New Cases Narrowing the Candidate Region and Review of the Literature.

Authors:  Ilaria Catusi; Maria Garzo; Anna Paola Capra; Silvana Briuglia; Chiara Baldo; Maria Paola Canevini; Rachele Cantone; Flaviana Elia; Francesca Forzano; Ornella Galesi; Enrico Grosso; Michela Malacarne; Angela Peron; Corrado Romano; Monica Saccani; Lidia Larizza; Maria Paola Recalcati
Journal:  Genes (Basel)       Date:  2021-04-27       Impact factor: 4.096

3.  Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism.

Authors:  Michael S Breen; Andrew Browne; Gabriel E Hoffman; Sofia Stathopoulos; Kristen Brennand; Joseph D Buxbaum; Elodie Drapeau
Journal:  Mol Autism       Date:  2020-06-19       Impact factor: 7.509

Review 4.  Balancing serendipity and reproducibility: Pluripotent stem cells as experimental systems for intellectual and developmental disorders.

Authors:  Nickesha C Anderson; Pin-Fang Chen; Kesavan Meganathan; Wardiya Afshar Saber; Andrew J Petersen; Anita Bhattacharyya; Kristen L Kroll; Mustafa Sahin
Journal:  Stem Cell Reports       Date:  2021-04-15       Impact factor: 7.765

Review 5.  Episodic Ataxias: Faux or Real?

Authors:  Paola Giunti; Elide Mantuano; Marina Frontali
Journal:  Int J Mol Sci       Date:  2020-09-05       Impact factor: 5.923

  5 in total

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