David M Rosen1, Vaishnavi Kundel2, Michael Rueschman3, Robert Kaplan4,5, Na Guo3, James G Wilson6, Yuan-I Min7, Susan Redline3, Neomi Shah8,9. 1. Division of Pulmonary and Critical Care Medicine, The Valley Hospital, Ridgewood, NJ, USA. 2. Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1232, New York, NY, 10029, USA. 3. Brigham and Women's Hospital, Division of Sleep and Circadian Disorders, Harvard Medical School, Boston, MA, USA. 4. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA. 5. Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. 6. Department of Physiology, The University of Mississippi Medical Center, Jackson, MS, USA. 7. School of Medicine, The University of Mississippi Medical Center, Jackson, MS, USA. 8. Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1232, New York, NY, 10029, USA. neomi.shah@mssm.edu. 9. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA. neomi.shah@mssm.edu.
Abstract
PURPOSE: Evidence suggests that snoring is associated with increased risk for cardiovascular disease (CVD) events such as myocardial infarction and stroke. Limited data exists pertaining to this association among African Americans. We therefore examined the association between self-reported habitual snoring and incident CVD in the Jackson Heart Study (JHS), a population-based cohort study of African Americans. METHODS: Self-reported data on snoring and risk factors for CVD were collected at baseline (2000-2004). Participants were followed prospectively for the development of incident CVD. Habitual snoring was defined as present if the participants reported it as "often" or "almost always" or absent if reported as "sometimes," "never," or "seldom." A CVD event included stroke, myocardial infarction, coronary revascularization procedure, or fatal CHD event. Cox proportional hazards models assessed the independent association between self-reported habitual snoring and incident CVD event adjusting for multiple covariates, including age, sex, hypertension, body mass index, diabetes, hypercholesterolemia, and smoking status. RESULTS: The snorer group consisted of 787 participants (mean age 52.1 years) and the nonsnorer group consisted of 3708 participants (mean age 54.9 years). Frequency of incident CVD events in the snorer group was not significantly different from the nonsnorer group. The fully adjusted hazard ratio for a CVD event in the snorer group was 1.01 (95% confidence interval [0.69, 1.47], p value of 0.96). CONCLUSION: In conclusion, self-reported habitual snoring was not associated with incident CVD among this large African American cohort. Future studies providing objective data on snoring and sleep apnea may provide more information on the snoring-CVD association among African Americans. TRIAL REGISTRATION: Identification Number: NCT00005485.
PURPOSE: Evidence suggests that snoring is associated with increased risk for cardiovascular disease (CVD) events such as myocardial infarction and stroke. Limited data exists pertaining to this association among African Americans. We therefore examined the association between self-reported habitual snoring and incident CVD in the Jackson Heart Study (JHS), a population-based cohort study of African Americans. METHODS: Self-reported data on snoring and risk factors for CVD were collected at baseline (2000-2004). Participants were followed prospectively for the development of incident CVD. Habitual snoring was defined as present if the participants reported it as "often" or "almost always" or absent if reported as "sometimes," "never," or "seldom." A CVD event included stroke, myocardial infarction, coronary revascularization procedure, or fatal CHD event. Cox proportional hazards models assessed the independent association between self-reported habitual snoring and incident CVD event adjusting for multiple covariates, including age, sex, hypertension, body mass index, diabetes, hypercholesterolemia, and smoking status. RESULTS: The snorer group consisted of 787 participants (mean age 52.1 years) and the nonsnorer group consisted of 3708 participants (mean age 54.9 years). Frequency of incident CVD events in the snorer group was not significantly different from the nonsnorer group. The fully adjusted hazard ratio for a CVD event in the snorer group was 1.01 (95% confidence interval [0.69, 1.47], p value of 0.96). CONCLUSION: In conclusion, self-reported habitual snoring was not associated with incident CVD among this large African American cohort. Future studies providing objective data on snoring and sleep apnea may provide more information on the snoring-CVD association among African Americans. TRIAL REGISTRATION: Identification Number: NCT00005485.
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