Literature DB >> 30753821

The Origin of CIMP, At Last.

Toshikazu Ushijima1, Hiromu Suzuki2.   

Abstract

In this issue of Cancer Cell, Tao et al. provide compelling evidence that aging-like DNA methylation of multiple CpG islands, the CpG island methylator phenotype (CIMP), produces a cellular context that can tolerate BRAF activation avoiding senescence by dedicating 5-month culture of colon-derived organoids to epigenomic and stemness analysis.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID： 30753821     DOI： 10.1016/j.ccell.2019.01.015

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  3 in total

1.  DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation.

Authors:  Douglas J MacKenzie; Neil A Robertson; Iqbal Rather; Claire Reid; Gintare Sendzikaite; Hazel Cruickshanks; Tony McBryan; Andrew Hodges; Catrin Pritchard; Karen Blyth; Peter D Adams
Journal:  iScience       Date:  2020-01-14

2.  Combination of artificial intelligence-based endoscopy and miR148a methylation for gastric indefinite dysplasia diagnosis.

Authors:  Yoshiyuki Watanabe; Ritsuko Oikawa; Shuhei Agawa; Yasumasa Matsuo; Ichiro Oda; Seiji Futagami; Hiroyuki Yamamoto; Tomohiro Tada; Fumio Itoh
Journal:  J Clin Lab Anal       Date:  2021-11-22       Impact factor: 2.352

3.  The Differential DNA Hypermethylation Patterns of microRNA-137 and microRNA-342 Locus in Early Colorectal Lesions and Tumours.

Authors:  Elham Kashani; Mahrooyeh Hadizadeh; Vahid Chaleshi; Reza Mirfakhraie; Chris Young; Sanaz Savabkar; Shiva Irani; Hamid Asadzadeh Aghdaei; Maziar Ashrafian Bonab
Journal:  Biomolecules       Date:  2019-09-21
  3 in total

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