You La Jeon 1 , Woo-In Lee 2,1 , So Young Kang 2,1 , Myeong Hee Kim 2,1 Show Affiliations »
Abstract
OBJECTIVE: To determine whether NMLR has more statistical strength than NLR in discriminating TB from non-TB infectious lung diseases. METHODS: Among patients who underwent 3 or more TB culture tests with molecular study between January 2016 and December 2017, 110 patients with TB, and 159 patients diagnosed with non-TB infectious lung diseases were enrolled. The original complete blood count (CBC) parameters and modified CBC indices, including NLR and NMLR, were analyzed. RESULTS: The NLR and NMLR were significantly lower in TB patients than in patients with other infectious lung diseases. However, the area under the curve (AUC) for NMLR (0.90; 95% confidence interval [CI], 0.86-0.93) was significantly greater than that for NLR (0.88 [0.84-0.92]). CONCLUSIONS: The neutrophil-to-monocyte-plus-lymphocyte ratio (NMLR) can be used as a new index that is more powerful than neutrophil-to-lymphocyte ratio (NLR) in discriminating tuberculosis (TB) from non-TB infectious lung diseases.NMLR had more statistical strength than NLR in discriminating TB from non-TB infectious lung diseases. © American Society for Clinical Pathology, 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
OBJECTIVE: To determine whether NMLR has more statistical strength than NLR in discriminating TB from non-TB infectious lung diseases . METHODS: Among patients who underwent 3 or more TB culture tests with molecular study between January 2016 and December 2017, 110 patients with TB, and 159 patients diagnosed with non-TB infectious lung diseases were enrolled. The original complete blood count (CBC) parameters and modified CBC indices, including NLR and NMLR, were analyzed. RESULTS: The NLR and NMLR were significantly lower in TB patients than in patients with other infectious lung diseases . However, the area under the curve (AUC) for NMLR (0.90; 95% confidence interval [CI], 0.86-0.93) was significantly greater than that for NLR (0.88 [0.84-0.92]). CONCLUSIONS: The neutrophil-to-monocyte-plus-lymphocyte ratio (NMLR) can be used as a new index that is more powerful than neutrophil-to-lymphocyte ratio (NLR) in discriminating tuberculosis (TB) from non-TB infectious lung diseases .NMLR had more statistical strength than NLR in discriminating TB from non-TB infectious lung diseases . © American Society for Clinical Pathology, 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Entities: Disease
Species
Keywords:
complete blood cell count; infectious lung diseases; neutrophil-to-lymphocyte ratio; neutrophil-to-monocyte-plus-lymphocyte ratio; pneumonia; tuberculosis
Year: 2019
PMID： 30753566 DOI： 10.1093/labmed/lmy083
Source DB: PubMed Journal: Lab Med ISSN： 0007-5027