Literature DB >> 3074621

Calcium antagonists as a peripherally acting labyrinthine suppressant in humans.

P L Mangabeira-Albernaz1.   

Abstract

A total of 908 patients with peripheral vestibular disorders were treated with calcium antagonists for periods of 10 to 120 days in a series of controlled clinical trials using a placebo or other medication for comparison. The cumulative analysis of the results indicates that cinnarizine, flunarizine and bencyclan have produced good clinical results, particularly in patients with vascular problems. A comparison between different doses used in different trials revealed a correlation of good clinical results to smaller doses of some of these medications.

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Year:  1988        PMID： 3074621     DOI： 10.3109/00016488809125142

Source DB:  PubMed          Journal:  Acta Otolaryngol Suppl        ISSN： 0365-5237


  3 in total

1.  Effect of the novel histamine H4 receptor antagonist SENS-111 on spontaneous nystagmus in a rat model of acute unilateral vestibular loss.

Authors:  Mathieu Petremann; Cindy Gueguen; Viviana Delgado Betancourt; Eric Wersinger; Jonas Dyhrfjeld-Johnsen
Journal:  Br J Pharmacol       Date:  2019-08-28       Impact factor: 8.739

2.  Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modelling of the novel H4 receptor inhibitor SENS-111 using a modified caloric test in healthy subjects.

Authors:  Frédéric Venail; Pierre Attali; Eric Wersinger; Roberto Gomeni; Sonia Poli; Sebastien Schmerber
Journal:  Br J Clin Pharmacol       Date:  2018-10-01       Impact factor: 4.335

3.  Optimizing the pharmacological component of integrated balance therapy.

Authors:  Maurício Malavasi Ganança; Heloisa Helena Caovilla; Mário Sérgio Lei Munhoz; Cristina Freitas Ganança; Maria Leonor Garcia da Silva; Flavio Serafini; Fernando Freitas Ganança
Journal:  Braz J Otorhinolaryngol       Date:  2007 Jan-Feb
  3 in total

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