Literature DB >> 30746012

Novel Oral Anticoagulants as Treatment for Vertebral Artery Dissection: Case Report.

Fernando Góngora-Rivera1,2, Héctor R Martínez1,2, Leonel Cantu-Martinez2, Carlos R Camara-Lemarroy1, Talía Moreno-Andrade1.   

Abstract

BACKGROUND AND
PURPOSE: Cervical artery dissections, which may be traumatic or spontaneous, account for a significant proportion of strokes in the young. Antithrombotic therapy is the mainstay of treatment, but new oral anticoagulants could be an alternative treatment to the optimal strategy of anticoagulation followed by antiplatelet drugs. SUMMARY OF CASE: We report the case of a 40-year-old patient with a spontaneous vertebral artery dissection who developed a cerebellar ischemic stroke, who had a favorable outcome and complete vessel recanalization after three months of treatment with the oral factor Xa inhibitor rivaroxaban.
CONCLUSION: New oral anticoagulant could constitute an alternative and new therapeutic option in cervical artery dissections.

Entities:  

Keywords:  Anticoagulation; stroke; vertebrobasilar disease

Year:  2018        PMID: 30746012      PMCID: PMC6350868     

Source DB:  PubMed          Journal:  J Vasc Interv Neurol        ISSN: 1941-5893


  10 in total

Review 1.  Spontaneous cervical and cerebral arterial dissections: diagnosis and management.

Authors:  Rudy J Rahme; Salah G Aoun; Jamal McClendon; Tarek Y El Ahmadieh; Bernard R Bendok
Journal:  Neuroimaging Clin N Am       Date:  2013-05-17       Impact factor: 2.264

2.  Arterial antithrombotic activity of rivaroxaban, an orally active factor Xa inhibitor, in a rat electrolytic carotid artery injury model of thrombosis.

Authors:  Tom J Parry; Zhihong Huang; Cailin Chen; Margery A Connelly; Elisabeth Perzborn; Patricia Andrade-Gordon; Bruce P Damiano
Journal:  Blood Coagul Fibrinolysis       Date:  2011-12       Impact factor: 1.276

3.  Rivaroxaban attenuates leukocyte adhesion in the microvasculature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus.

Authors:  Toshiaki Iba; Koichiro Aihara; Atushi Yamada; Masataka Nagayama; Yoko Tabe; Akimichi Ohsaka
Journal:  Thromb Res       Date:  2013-11-25       Impact factor: 3.944

4.  Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial.

Authors:  Hugh S Markus; Elizabeth Hayter; Christopher Levi; Adina Feldman; Graham Venables; John Norris
Journal:  Lancet Neurol       Date:  2015-02-12       Impact factor: 44.182

Review 5.  Clinical characteristics of symptomatic vertebral artery dissection: a systematic review.

Authors:  Rebecca F Gottesman; Priti Sharma; Karen A Robinson; Martinson Arnan; Megan Tsui; Karim Ladha; David E Newman-Toker
Journal:  Neurologist       Date:  2012-09       Impact factor: 1.398

6.  Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Authors:  Walter N Kernan; Bruce Ovbiagele; Henry R Black; Dawn M Bravata; Marc I Chimowitz; Michael D Ezekowitz; Margaret C Fang; Marc Fisher; Karen L Furie; Donald V Heck; S Claiborne Clay Johnston; Scott E Kasner; Steven J Kittner; Pamela H Mitchell; Michael W Rich; DeJuran Richardson; Lee H Schwamm; John A Wilson
Journal:  Stroke       Date:  2014-05-01       Impact factor: 7.914

Review 7.  Cerebrovascular dissections--a review part I: Spontaneous dissections.

Authors:  Matthew R Fusco; Mark R Harrigan
Journal:  Neurosurgery       Date:  2011-01       Impact factor: 4.654

Review 8.  Rivaroxaban in acute coronary syndromes--is it prime time?

Authors:  Muhammad Asrar ul Haq; William J van Gaal
Journal:  Expert Rev Cardiovasc Ther       Date:  2014-04-19

Review 9.  Current optimal assessment and management of carotid and vertebral spontaneous and traumatic dissection.

Authors:  Irwin V Mohan
Journal:  Angiology       Date:  2013-02-11       Impact factor: 3.619

Review 10.  Antiplatelets versus anticoagulants for the treatment of cervical artery dissection: Bayesian meta-analysis.

Authors:  Hakan Sarikaya; Bruno R da Costa; Ralf W Baumgartner; Kathleen Duclos; Emmanuel Touzé; Jean M de Bray; Antti Metso; Tiina Metso; Marcel Arnold; Antonio Arauz; Marcel Zwahlen; Peter Jüni
Journal:  PLoS One       Date:  2013-09-05       Impact factor: 3.240

  10 in total

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