Literature DB >> 30743093

Priorities and recommended actions for how researchers, practitioners, policy makers, and the affected community can work together to improve access to hepatitis C care for people who use drugs.

Emma Day1, Tina Broder2, Julie Bruneau3, Sally Cruse1, Melisa Dickie4, Suzanne Fish4, Celine Grillon5, Niklas Luhmann5, Kate Mason6, Elizabeth McLean7, Stacey Trooskin8, Carla Treloar9, Jason Grebely10.   

Abstract

It is estimated that 6.1 million people with recent injecting drug use (PWID) are living with hepatitis C virus (HCV). Although HCV-related morbidity and mortality among PWID continues to increase, the advent of direct acting antiviral (DAA) HCV regimens with cure rates >95% provides an opportunity to reverse the rising burden of disease. Additionally, given evidence that opioid substitution therapy and high-coverage needle and syringe programs can reduce HCV incidence by up to 80%, there is an opportunity to reduce HCV transmission with increased coverage of harm reduction services. However, there are significant patient, provider, health system, structural, and societal barriers that impede access to HCV prevention and care for PWID. The International Network on Hepatitis in Substance Users (INHSU), in collaboration with the Australasian Society for HIV, Viral Hepatitis, Sexual Health Medicine (ASHM), Harm Reduction International, the Canadian Network on Hepatitis C, Canadian Research Initiative in Substance Misuse, the National Viral Hepatitis Roundtable, Médecins du Monde and CATIE, held a roundtable discussion prior to the Harm Reduction Conference in Montreal, Canada on 13th May 2017 to discuss how to improve HCV prevention and care for PWID. Over 100 international researchers, practitioners, policy makers, advocates, and affected community members came together to discuss shared priorities for action, develop actionable next steps and to create partnerships to enable application of priorities. This paper highlights the key priority areas identified by participants including: enhancing global coverage of harm reduction services; addressing punitive drug policies; ensuring access to affordable HCV diagnostics and treatment; improving the evidence-base for HCV prevention, testing, linkage to care and treatment; implementing integrated HCV programs; advancing peer-based models of HCV care; and tackling social determinants of health inequalities for PWID. This paper also highlights the recommended actions for each priority identified by the participants from this roundtable.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Direct acting antiviral (DAA) treatment; HCV; Harm reduction; Hepatitis C; Models of care; Needle and syringe programs (NSP); Opioid substitution therapy (OST); PWID

Mesh:

Substances:

Year:  2019        PMID: 30743093     DOI: 10.1016/j.drugpo.2019.01.012

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  9 in total

1.  Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: a systematic integrative review.

Authors:  Katrina Bouzanis; Siddharth Joshi; Cynthia Lokker; Sureka Pavalagantharajah; Yun Qiu; Hargun Sidhu; Lawrence Mbuagbaw; Majdi Qutob; Alia Henedi; Mitchell A H Levine; Robin Lennox; Jean-Eric Tarride; Dale Kalina; Elizabeth Alvarez
Journal:  BMJ Open       Date:  2021-09-23       Impact factor: 3.006

2.  A cascade of care analysis on the elimination of hepatitis C from public hospitals in Madrid.

Authors:  José Luis Calleja; Javier García-Samaniego; Jeffrey V Lazarus; Marcela Villota-Rivas; Inmaculada Fernández; Francisco Gea; Pablo Ryan; Sonia Alonso López; Danielle Guy
Journal:  Commun Med (Lond)       Date:  2022-02-24

3.  Psychosocial Factors and the Care Cascade for Hepatitis C Treatment Colocated at a Syringe Service Program.

Authors:  Daniel Winetsky; Daniel Burack; Pantelis Antoniou; Bill Garcia; Peter Gordon; Matthew Scherer
Journal:  J Infect Dis       Date:  2020-09-02       Impact factor: 5.226

4.  "Stigma is where the harm comes from": Exploring expectations and lived experiences of hepatitis C virus post-treatment trajectories among people who inject drugs.

Authors:  Trevor Goodyear; Helen Brown; Annette J Browne; Peter Hoong; Lianping Ti; Rod Knight
Journal:  Int J Drug Policy       Date:  2021-04-23

5.  HIV Prevention Trials Network 078: High Prevalence of Hepatitis C Virus Antibodies Among Urban US Men Who Have Sex With Men, Independent of Human Immunodeficiency Virus Status.

Authors:  Risha Irvin; Theresa Gamble; Jowanna Malone; Zhe Wang; Ethan Wilson; James P Hughes; Jason Farley; Kenneth H Mayer; Carlos Del Rio; D Scott Batey; Vanessa Cummings; Robert H Remien; Chris Beyrer; Chloe L Thio
Journal:  Clin Infect Dis       Date:  2021-10-05       Impact factor: 20.999

6.  An Investigation of the Side Effects, Patient Feedback, and Physiological Changes Associated with Direct-Acting Antiviral Therapy for Hepatitis C.

Authors:  Pin-Sheng Wu; Te-Sheng Chang; Sheng-Nan Lu; Hsiang-Jou Su; Shu-Zhi Chang; Chia-Wen Hsu; Mei-Yen Chen
Journal:  Int J Environ Res Public Health       Date:  2019-12-07       Impact factor: 3.390

7.  Direct-Acting Antiviral Treatment Use Remains Low Among Florida Medicaid Beneficiaries With Chronic Hepatitis C.

Authors:  Haesuk Park; Hyun Jin Song; Xinyi Jiang; Linda Henry; Robert L Cook; David R Nelson
Journal:  Hepatol Commun       Date:  2020-11-17

8.  Could 30 years of political controversy on needle exchange programmes in Sweden contribute to scaling-up harm reduction services in the world?

Authors:  Niklas Karlsson; Torsten Berglund; Anna Mia Ekström; Anders Hammarberg; Tuukka Tammi
Journal:  Nordisk Alkohol Nark       Date:  2020-12-17

9.  Reaching Hard-to-Reach People Who Use Drugs: A Community-Based Strategy for the Elimination of Hepatitis C.

Authors:  Nicolas Nagot; Morgana D'Ottavi; Catherine Quillet; Anne Debellefontaine; Joëlle Castellani; Nicolas Langendorfer; Bertrand Hanslik; Sylvain Guichard; René Baglioni; Vincent Faucherre; Edouard Tuaillon; Georges-Philippe Pageaux; Didier Laureillard; Hélène Donnadieu-Rigole
Journal:  Open Forum Infect Dis       Date:  2022-04-14       Impact factor: 4.423

  9 in total

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