Literature DB >> 30742139

Designing redder and brighter fluorophores by synergistic tuning of ground and excited states.

Cheng Chen1, Mikhail S Baranov, Liangdong Zhu, Nadezhda S Baleeva, Alexander Yu Smirnov, Snizhana O Zaitseva, Ilia V Yampolsky, Kyril M Solntsev, Chong Fang.   

Abstract

We strategically modified the GFP core via chemical synthesis to make redder and brighter biomimetic fluorophores. Based on quantum calculations, solvatochromism analysis, and femtosecond Raman, we unveiled the additive effect of tuning the electronic ground and excited states, respectively, to achieve a dramatic emission redshift with a "double-donor-one-acceptor" structure.

Entities:  

Year:  2019        PMID： 30742139     DOI： 10.1039/c8cc10007a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Fluorescent Orthopalladated Complexes of 4-Aryliden-5(4H)-oxazolones from the Kaede Protein: Synthesis and Characterization.

Authors:  Eduardo Laga; David Dalmau; Sofía Arregui; Olga Crespo; Ana I Jimenez; Alexandra Pop; Cristian Silvestru; Esteban P Urriolabeitia
Journal:  Molecules       Date:  2021-02-25       Impact factor: 4.411

2.  De novo generation of a bright blue fluorophore from 2-oxoglutarate in biological samples.

Authors:  Yumin Kim; Sangyoon Kang; Byung Hun Lee; Youngjun Song; Sunah Kang; Hye Yoon Park; Yan Lee
Journal:  Chem Sci       Date:  2021-12-07       Impact factor: 9.825

3.  Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization.

Authors:  Cheng Chen; Jasmine N Tutol; Longteng Tang; Liangdong Zhu; Whitney S Y Ong; Sheel C Dodani; Chong Fang
Journal:  Chem Sci       Date:  2021-07-21       Impact factor: 9.969
  3 in total

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