Müzeyyen Iyigun1, Güclü Aykut2, Melis Tosun1, Meltem Kilercik3, Ugur Aksu4, Tayfun Güler1, Fevzi Toraman5. 1. Department of Anesthesiology and Reanimation, School of Medicine, Acibadem Mehmet Ali Aydınlar University, Istanbul, Turkey. 2. Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany. 3. Department of Clinical Biochemistry, School of Medicine, Acibadem Mehmet Ali Aydınlar University, Istanbul, Turkey. 4. Department of Biology, Faculty of Science, University of Istanbul, Istanbul, Turkey. 5. Department of Anesthesiology and Reanimation, School of Medicine, Acibadem Mehmet Ali Aydınlar University, Istanbul, Turkey. Electronic address: ftoraman@gmail.com.
Abstract
BACKGROUND: The aim of this study was to determine the incidence and the perioperative risk factors of acute kidney injury (AKI) using "Kidney Disease: Improving Global Outcomes" (KDIGO) guidelines, in patients with low grade American Society of Anesthesiologists physical status (ASA-PS) undergoing non-cardiac surgery. METHODS: In this multicenter, prospective, observational study, 870 surgical patients older than 40 years with ASA-PS I-II who underwent noncardiac surgery, were included. The primary outcome of this study was perioperative AKI defined by the KDIGO criteria. RESULTS: AKI was detected in 49 (5.63%) of the patients. Multivariate analysis detected the presence of preoperative hypertension (aOR = 0.130; CI = 0.030-0.566; p = 0.007) and intraoperative transfusion of erythrocytes (aOR = 0.076; CI = 0.008-0.752; p = 0.028) as independent predictors of postoperative AKI development. CONCLUSION: Approximately, 6% of patients with ASA I-II presenting for noncardiac surgery developed postoperative AKI. Preoperative hypertension and intraoperative erythrocyte transfusion are independent predictors of AKI after non-cardiac surgery in this patient population.
BACKGROUND: The aim of this study was to determine the incidence and the perioperative risk factors of acute kidney injury (AKI) using "Kidney Disease: Improving Global Outcomes" (KDIGO) guidelines, in patients with low grade American Society of Anesthesiologists physical status (ASA-PS) undergoing non-cardiac surgery. METHODS: In this multicenter, prospective, observational study, 870 surgical patients older than 40 years with ASA-PS I-II who underwent noncardiac surgery, were included. The primary outcome of this study was perioperative AKI defined by the KDIGO criteria. RESULTS: AKI was detected in 49 (5.63%) of the patients. Multivariate analysis detected the presence of preoperative hypertension (aOR = 0.130; CI = 0.030-0.566; p = 0.007) and intraoperative transfusion of erythrocytes (aOR = 0.076; CI = 0.008-0.752; p = 0.028) as independent predictors of postoperative AKI development. CONCLUSION: Approximately, 6% of patients with ASA I-II presenting for noncardiac surgery developed postoperative AKI. Preoperative hypertension and intraoperative erythrocyte transfusion are independent predictors of AKI after non-cardiac surgery in this patient population.
Authors: Dilshan Ariyarathna; Ajinkya Bhonsle; Joseph Nim; Colin K L Huang; Gabriella H Wong; Nicholle Sim; Joy Hong; Kirrolos Nan; Andy K H Lim Journal: Ren Fail Date: 2022-12 Impact factor: 3.222
Authors: Gianluca Villa; Silvia De Rosa; Caterina Scirè Calabrisotto; Alessandro Nerini; Thomas Saitta; Dario Degl'Innocenti; Laura Paparella; Vittorio Bocciero; Marco Allinovi; Angelo R De Gaudio; Marlies Ostermann; Stefano Romagnoli Journal: Perioper Med (Lond) Date: 2021-05-25