Eileen G Collins1,2, Christine Jelinek3, Susan O'Connell3, Jolene Butler3, Domenic Reda4,5, Franco Laghi6,7. 1. Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA. ecollins@uic.edu. 2. Physical Performance Laboratory, Research & Development Service, Edward Hines Jr. Veterans Affairs Hospital, Hines, IL, USA. ecollins@uic.edu. 3. Physical Performance Laboratory, Research & Development Service, Edward Hines Jr. Veterans Affairs Hospital, Hines, IL, USA. 4. VA Cooperative Studies Program Coordinating Center, Edward Hines Jr, Veterans Affairs Hospital, Hines, IL, USA. 5. School of Public Health, University of Illinois at Chicago, Chicago, IL, USA. 6. Stritch School of Medicine, Loyola University, Maywood, IL, USA. 7. Pulmonary Medicine, Department of Medicine, Edward Hines Jr, VA Hospital, Hines, IL, USA.
Abstract
BACKGROUND: During exercise-trainingpatients with chronic obstructive pulmonary disease (COPD) can entrain their breathing pattern to visual-feedback cues as to achieve a slower respiratory rate and prolong exhalation. The result is an improvement in exercise tolerance and a reduction in dynamic hyperinflation. Acoustic stimuli, including metronome-generated acoustic stimuli, can entrain human movements. Accordingly, we hypothesized that exercise duration and dynamic hyperinflation would be less after exercise-training plus breathing-retraining using a metronome-based acoustic-feedback system than after exercise-training alone. METHODS: Of 205 patients with COPD [FEV1 = 44 ± 16% predicted (± SD)] recruited, 119 were randomly assigned to exercise-training plus breathing-retraining using acoustic feedback (n = 58) or exercise-training alone (n = 61). Patients exercised on a treadmill thrice-weekly for 12 weeks. Before and at completion of training, patients underwent constant-load treadmill testing with inspiratory capacity measures every 2 min. RESULTS: At completion of training, improvements in exercise duration in the breathing-retraining plus exercise-training and exercise-training alone groups were similar (p = 0.35). At isotime, inspiratory capacity increased (less exercise-induced dynamic hyperinflation) by 3% (p = 0.001) in the breathing-retraining plus exercise-training group and remained unchanged in the exercise-alone group. The between-group change in inspiratory capacity, however, was not significant (p = 0.08). CONCLUSIONS: In patients with COPD, breathing-retraining using a metronome-based acoustic feedback did not result in improved exercise endurance or decreased dynamic hyperinflation when compared to exercise-training alone. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT NCT01009099; URL: http://www.clinicaltrials.gov.
RCT Entities:
BACKGROUND: During exercise-training patients with chronic obstructive pulmonary disease (COPD) can entrain their breathing pattern to visual-feedback cues as to achieve a slower respiratory rate and prolong exhalation. The result is an improvement in exercise tolerance and a reduction in dynamic hyperinflation. Acoustic stimuli, including metronome-generated acoustic stimuli, can entrain human movements. Accordingly, we hypothesized that exercise duration and dynamic hyperinflation would be less after exercise-training plus breathing-retraining using a metronome-based acoustic-feedback system than after exercise-training alone. METHODS: Of 205 patients with COPD [FEV1 = 44 ± 16% predicted (± SD)] recruited, 119 were randomly assigned to exercise-training plus breathing-retraining using acoustic feedback (n = 58) or exercise-training alone (n = 61). Patients exercised on a treadmill thrice-weekly for 12 weeks. Before and at completion of training, patients underwent constant-load treadmill testing with inspiratory capacity measures every 2 min. RESULTS: At completion of training, improvements in exercise duration in the breathing-retraining plus exercise-training and exercise-training alone groups were similar (p = 0.35). At isotime, inspiratory capacity increased (less exercise-induced dynamic hyperinflation) by 3% (p = 0.001) in the breathing-retraining plus exercise-training group and remained unchanged in the exercise-alone group. The between-group change in inspiratory capacity, however, was not significant (p = 0.08). CONCLUSIONS: In patients with COPD, breathing-retraining using a metronome-based acoustic feedback did not result in improved exercise endurance or decreased dynamic hyperinflation when compared to exercise-training alone. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT NCT01009099; URL: http://www.clinicaltrials.gov.
Authors: Francisco Ortega; Javier Toral; Pilar Cejudo; Rafael Villagomez; Hildegard Sánchez; José Castillo; Teodoro Montemayor Journal: Am J Respir Crit Care Med Date: 2002-09-01 Impact factor: 21.405
Authors: Eileen G Collins; W Edwin Langbein; Linda Fehr; Susan O'Connell; Christine Jelinek; Eileen Hagarty; Lonnie Edwards; Domenic Reda; Martin J Tobin; Franco Laghi Journal: Am J Respir Crit Care Med Date: 2008-01-17 Impact factor: 21.405
Authors: Charlotte C Poot; Eline Meijer; Annemarije L Kruis; Nynke Smidt; Niels H Chavannes; Persijn J Honkoop Journal: Cochrane Database Syst Rev Date: 2021-09-08