Enhanced potential of biomimetic, silver nanoparticles functionalized Antheraea mylitta (tasar) silk fibroin nanofibrous mats for skin tissue engineering.

In the present study, we have successfully prepared tasar fibroin nanofibrous mats using 1‑butyl‑3‑methylimidazolium acetate for skin tissue engineering. The prepared tasar nanofibrous mat was further coated by silver nanoparticles (AgNPs) in situ using dandelion (Tridax procumbens) leaf extract. The kinetic of silver nanoparticles formation was studied by UV-VIS spectrophotometer. The prepared silver nanoparticles were further confirmed by XRD and TEM. The coating of tasar nanofibrous mat with silver nanoparticles was confirmed by EDX and EDX mapping techniques. The physical, mechanical, antimicrobial and biological properties of these silver nanoparticles coated tasar nanofibrous mat were determined in order to check its suitability for skin tissue engineering and wound dressing applications.