| Literature DB >> 30737268 |
Wen-Qian Chen1, Colleen Drapek2, Dong-Xu Li1, Zhi-Hong Xu1, Philip N Benfey2, Shu-Nong Bai3.
Abstract
The Arabidopsis (Arabidopsis thaliana) root epidermis is a simple model for investigating cell fate specification and pattern formation. In addition to regulatory networks consisting of transcription factors, histone deacetylases are also involved in the formation of cellular patterns. Here, we report thatHistone Deacetylase19 (HDA19) affects the root epidermal cellular pattern through regulation of cortical cell fate by interacting with SCARECROW (SCR). HDA19 binds to the DNA sequence upstream of SCR, as well as to those of several of SCR's target genes, and regulates their expression. Mutant lines of several SCR target genes show impaired patterns of epidermal differentiation and cortical cell division, similar to that of hda19 This work presents HDA19 and SCR as two further players in the regulation of cortical and epidermal cell specification and describes an additional function for SCR.Entities:
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Year: 2019 PMID： 30737268 PMCID： PMC6501111 DOI： 10.1104/pp.19.00056
Source DB: PubMed Journal: Plant Physiol ISSN： 0032-0889 Impact factor: 8.340