| Literature DB >> 30737128 |
Paola Scognamiglio1, Assunta Navarra2, Nicoletta Orchi1, Gabriella De Carli1, Silvia Pittalis3, Ilaria Mastrorosa4, Ubaldo Visco Comandini5, Chiara Agrati6, Andrea Antinori4, Vincenzo Puro1, Giuseppe Ippolito7, Enrico Girardi3.
Abstract
Treatment of chronic HCV infection with direct acting antivirals can achieve high rates of sustained viral response in persons with HIV. In the perspective of HCV elimination in this population, high rates of HCV detection will be needed. We evaluated the unawareness of HCV infection in 2927 persons newly diagnosed with HIV during 2004-2015 in Rome, Italy. Two-hundred-fifty persons (8.5%) were anti-HCV positive. The proportion of HCV-unaware individuals at the time of HIV diagnosis was 58.0% (145/250), without significant variations over time, 17.2% showed an advanced fibrosis stage. The absence of previous HIV testing was significantly associated with HCV unawareness.Entities:
Keywords: HCV; HIV-HCV coinfection; Hepatitis; Italy; Late diagnosis
Mesh：
Year: 2019 PMID： 30737128 DOI： 10.1016/j.jiph.2019.01.055
Source DB: PubMed Journal: J Infect Public Health ISSN： 1876-0341 Impact factor: 3.718