Caterina Calderon1, Alberto Carmona-Bayonas2, Raquel Hernández3, Ismael Ghanem4, Beatriz Castelo4, Eva Martinez de Castro5, Estrella Ferreira6, Laura Ciria6, María Muñiz7, Paula Jimenez-Fonseca7. 1. Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Spain. Electronic address: ccalderon@ub.edu. 2. Department of Medical Oncology, Hospital Universitario Morales Meseguer, IMI, UMU, Murcia, Spain. 3. Department of Medical Oncology, Hospital Universitario of Canarias, Tenerife, Spain. 4. Department of Medical Oncology, Hospital Universitario The Paz, Madrid, Spain. 5. Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla Spain, Spain. 6. Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Spain. 7. Department of Medical Oncology, Hospital Universitario Central of Asturias, Oviedo, Spain.
Abstract
INTRODUCTION: The aim was to analyze the effects of pessimism, depression, fatigue, and pain on functional health-related quality of life (HRQoL) in patients with resected, non-advanced breast cancer. METHODS: A prospective, multicenter study was conducted in 440 breast cancer patients. They completed the Brief Symptom Inventory (BSI), the European Organization for Research and Treatment of Cancer QoL-Questionnaire-Core-30 (EORTC-QLQ-C30), and the Revised Life Orientation Test (LOT-R). RESULTS: Prevalence rates of pessimism and depression were 23.3% and 40.0%, respectively. Fatigue and pain were the most common symptoms, 8.8% and 4.2%, respectively. Patients without a partner were more pessimistic that partnered ones; those with a lower level of education and subjects without a partner exhibited more depression. Depression was a major factor that proved to have the greatest explanatory power for HRQoL (physical, role, emotional, cognitive, and social functioning) and global health status (R2 range: 0.13 to 0.39). Of the five domains, fatigue had a significant effect on four and pain, on two. CONCLUSION: This study reveals the impact of depression and pessimism on physical, psychological, social, and quality-of-life aspects and the importance of evaluating them in patients who are going to initiate adjuvant chemotherapy for breast cancer.
INTRODUCTION: The aim was to analyze the effects of pessimism, depression, fatigue, and pain on functional health-related quality of life (HRQoL) in patients with resected, non-advanced breast cancer. METHODS: A prospective, multicenter study was conducted in 440 breast cancerpatients. They completed the Brief Symptom Inventory (BSI), the European Organization for Research and Treatment of Cancer QoL-Questionnaire-Core-30 (EORTC-QLQ-C30), and the Revised Life Orientation Test (LOT-R). RESULTS: Prevalence rates of pessimism and depression were 23.3% and 40.0%, respectively. Fatigue and pain were the most common symptoms, 8.8% and 4.2%, respectively. Patients without a partner were more pessimistic that partnered ones; those with a lower level of education and subjects without a partner exhibited more depression. Depression was a major factor that proved to have the greatest explanatory power for HRQoL (physical, role, emotional, cognitive, and social functioning) and global health status (R2 range: 0.13 to 0.39). Of the five domains, fatigue had a significant effect on four and pain, on two. CONCLUSION: This study reveals the impact of depression and pessimism on physical, psychological, social, and quality-of-life aspects and the importance of evaluating them in patients who are going to initiate adjuvant chemotherapy for breast cancer.
Authors: Shiyu Jiang; Peng Liu; Sheng Yang; Jianliang Yang; Dawei Wu; Hong Fang; Yan Qin; Shengyu Zhou; Jianping Xu; Yongkun Sun; Hongnan Mo; Lin Gui; Puyuan Xing; Bo Lan; Bo Zhang; Le Tang; Yan Sun; Yuankai Shi Journal: BMJ Open Date: 2019-06-01 Impact factor: 2.692
Authors: Po-Chi Hsu; Han-Kuei Wu; Hen-Hong Chang; Jia-Ming Chen; John Y Chiang; Lun-Chien Lo Journal: Evid Based Complement Alternat Med Date: 2021-12-26 Impact factor: 2.629
Authors: Reina Haque; Jin Wen Hsu; Chantal Avila; Richard Olmstead; Judith E Carroll; Michael R Irwin Journal: J Womens Health (Larchmt) Date: 2020-10-09 Impact factor: 2.681
Authors: Laura Ciria-Suarez; Laura Costas; Aida Flix-Valle; Maria Serra-Blasco; Joan C Medina; Cristian Ochoa-Arnedo Journal: Cancers (Basel) Date: 2022-07-30 Impact factor: 6.575
Authors: Hannah M Fisher; Joseph G Winger; Shannon N Miller; Arianna N Wright; Jennifer C Plumb Vilardaga; Catherine Majestic; Sarah A Kelleher; Tamara J Somers Journal: Support Care Cancer Date: 2021-03-15 Impact factor: 3.603