Literature DB >> 30731461

Validation of Tokyo Guideline 2013 as Treatment of Acute Cholecystitis by Real World Data.

Shota Harai1, Hitoshi Mochizuki1, Yuichiro Kojima2, Keiko Nakagomi1, Dai Yoshimura1, Shinya Takaoka1, Kenji Hosoda1, Yoji Suzuki1, Masao Omata1,3.   

Abstract

BACKGROUND: The Tokyo Guidelines (TG; 2013) indicated that emergency cholecystectomy is an important early treatment option for acute cholecystitis; however, surgical intervention is not necessarily indicated in patients with advanced age. We evaluated percutaneous transhepatic gallbladder aspiration (PTGBA), percutaneous transhepatic gallbladder drainage (PTGBD), and the administration of antibiotics alone as treatment options for acute -cholecystitis.
METHODS: From January 2010 to December 2017, 159 patients with acute cholecystitis were treated at our institution. The data from these patients were retrospectively analyzed.
RESULTS: Of these 159 cases, 109 underwent PTGBA, 28 underwent PTGBD, and 22 were administered antibiotics alone. None of the 159 patients needed urgent (early) cholecystectomy, and all patients were discharged without mortality. PTGBA was unsuccessful in only 6 of 109 patients; PTGBD was performed in these 6 cases. Long-term follow-up was conducted in all cases. Of the 159 patients, 146 had gallbladder stones initially, while 13 had none at the time of presentation. Of these 146 patients with gallbladder stones, 84 underwent elective cholecystectomy, while 62 did not. Of the 84 patients who underwent elective cholecystectomy, 2 developed choledocholithiasis; of the 62 patients who did not undergo elective cholecystectomy, 5 developed choledocholithiasis and 2 developed acute cholecystitis. The incidences of choledocholithiasis and acute cholecystitis did not significantly differ between the 2 groups (p = 0.06).
CONCLUSIONS: Despite the recommendations in the TG (2013), emergency cholecystectomy was not needed in any of the present patients with acute cholecystitis. Acute cholecystitis can be successfully treated with -PTGBA or PTGBD, which are simple procedures with good short- and long-term safety. These procedures are highly recommended for patients with acute cholecystitis, especially in the elderly population.
© 2019 S. Karger AG, Basel.

Entities:  

Keywords:  Acute cholecystitis; Percutaneous transhepatic gallbladder aspiration; Percutaneous transhepatic gallbladder drainage

Mesh:

Year:  2019        PMID: 30731461     DOI: 10.1159/000496738

Source DB:  PubMed          Journal:  Dig Dis        ISSN: 0257-2753            Impact factor:   2.404


  3 in total

1.  Surgical outcome of percutaneous transhepatic gallbladder drainage in acute cholecystitis: Ten years' experience at a tertiary care centre.

Authors:  Szabolcs Ábrahám; Illés Tóth; Ria Benkő; Mária Matuz; Gabriella Kovács; Zita Morvay; András Nagy; Aurél Ottlakán; László Czakó; Zoltán Szepes; Dániel Váczi; András Négyessy; Attila Paszt; Zsolt Simonka; András Petri; György Lázár
Journal:  Surg Endosc       Date:  2021-08-20       Impact factor: 4.584

2.  Self-reported and actual adherence to the Tokyo guidelines in the European snapshot audit of complicated calculous biliary disease.

Authors:  G A Bass; A E Gillis; Y Cao; S Mohseni
Journal:  BJS Open       Date:  2020-05-17

3.  Patterns of prevalence and contemporary clinical management strategies in complicated acute biliary calculous disease: an ESTES 'snapshot audit' of practice.

Authors:  Gary Alan Bass; Amy Gillis; Yang Cao; Shahin Mohseni
Journal:  Eur J Trauma Emerg Surg       Date:  2020-07-07       Impact factor: 3.693

  3 in total

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