Literature DB >> 30730823

Exosomes: fighting cancer with cancer.

Hanin Alyamani1, Mohammad A Obeid2, Rothwelle J Tate1, Valerie A Ferro1.   

Abstract

Exosomes are nanovesicles secreted by many cells, including cancer cells. Extensive research has been carried out to validate potential applications of exosomes and to evaluate their efficiency in a wide range of diseases, including cancer. The current knowledge on the origin, biogenesis and composition of exosomes is described. This review then focuses on the use of exosomes in cancer diagnostics and therapeutics.

Entities:  

Keywords:  angiogenesis; cancer; diagnostic; exosomes; immune system; immunosuppression; miRNA; nucleic acid; progression; therapeutic

Mesh：

Substances：

Year:  2019        PMID： 30730823     DOI： 10.4155/tde-2018-0051

Source DB:  PubMed          Journal:  Ther Deliv        ISSN： 2041-5990


  5 in total

1.  Use of Nanoparticles in Delivery of Nucleic Acids for Melanoma Treatment.

Authors:  Mohammad A Obeid; Alaa A A Aljabali; Meriem Rezigue; Haneen Amawi; Hanin Alyamani; Shatha N Abdeljaber; Valerie A Ferro
Journal:  Methods Mol Biol       Date:  2021

2.  Extracellular vesicles containing PD-L1 contribute to CD8+ T-cell immune suppression and predict poor outcomes in small cell lung cancer.

Authors:  Xiaoyan Dou; Yan Hua; Zhaowu Chen; Fengmei Chao; Ming Li
Journal:  Clin Exp Immunol       Date:  2022-05-12       Impact factor: 5.732

Review 3.  microRNA and exosome profiling in multiple sclerosis.

Authors:  Marcin P Mycko; Sergio E Baranzini
Journal:  Mult Scler       Date:  2020-01-22       Impact factor: 6.312

4.  Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release.

Authors:  Mohammad A Obeid; Ibrahim Khadra; Abdullah Albaloushi; Margaret Mullin; Hanin Alyamani; Valerie A Ferro
Journal:  Beilstein J Nanotechnol       Date:  2019-09-05       Impact factor: 3.649

Review 5.  SARS-CoV-2: vaccinology and emerging therapeutics; challenges and future developments.

Authors:  Adedapo Adesokan; Mohammad A Obeid; Aisha F Lawal
Journal:  Ther Deliv       Date:  2022-02-23
  5 in total

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