Literature DB >> 30730356

Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV.

Lynae A Darbes1,2, Nuala M McGrath3,4, Victoria Hosegood4, Mallory O Johnson1, Katherine Fritz5, Thulani Ngubane6, Heidi van Rooyen7.   

Abstract

BACKGROUND: Although couples HIV testing and counseling (CHTC) is effective for facilitating mutual disclosure and linkage to HIV care, uptake remains low. Using a randomized controlled design, we tested the efficacy of a behavioral couples-based intervention aimed to increase CHTC.
SETTING: The Vulindlela district of KwaZulu-Natal, South Africa.
METHODS: Couples were recruited from the community (eg, markets and community events). Couples were excluded if mutual HIV serostatus disclosure had occurred. Both partners had to report being each other's primary partner and relationship length was at least 6 months. Assessments occurred at baseline, and 3, 6, and 9 months after intervention. Eligible couples attended a group session (3-4 hours) after which randomization occurred. Intervention couples additionally received: one couples-based group session followed by 4 couples' counseling sessions (1-2 hours). Intervention topics included communication skills, intimate partner violence, and HIV prevention. Our primary outcomes were CHTC and sexual risk behavior.
RESULTS: Overall, 334 couples were enrolled. Intervention couples were significantly more likely to have participated in CHTC [42% vs. 12% (P ≤ 0.001)]. In addition, their time to participate in CHTC was significantly shorter (logrank P ≤ 0.0001) (N = 332 couples). By group, 59% of those who tested HIV-positive in intervention and 40% of those who tested in control were new HIV diagnoses (P = 0.18). There were no group differences in unprotected sex.
CONCLUSIONS: Our intervention improved CHTC uptake-a vehicle for mutual serostatus disclosure and entrée into HIV treatment, both of which exert a significant public health impact on communities substantially burdened by HIV.

Entities:  

Mesh:

Year:  2019        PMID: 30730356      PMCID: PMC6524952          DOI: 10.1097/QAI.0000000000001948

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  31 in total

1.  Sexual behavior of HIV discordant couples after HIV counseling and testing.

Authors:  Susan Allen; Jareen Meinzen-Derr; Michele Kautzman; Isaac Zulu; Stanley Trask; Ulgen Fideli; Rosemary Musonda; Francis Kasolo; Feng Gao; Alan Haworth
Journal:  AIDS       Date:  2003-03-28       Impact factor: 4.177

2.  High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa.

Authors:  Frank Tanser; Till Bärnighausen; Erofili Grapsa; Jaffer Zaidi; Marie-Louise Newell
Journal:  Science       Date:  2013-02-22       Impact factor: 47.728

3.  Feasibility and acceptability of Project Connect: a couples-based HIV-risk reduction intervention among young couples in Johannesburg, South Africa.

Authors:  Audrey Pettifor; Catherine MacPhail; Nadia Nguyen; Molly Rosenberg; Lisa Parker; Jabu Sibeko
Journal:  AIDS Care       Date:  2013-10-14

4.  Preventing marital distress through communication and conflict management training: a 4- and 5-year follow-up.

Authors:  H J Markman; M J Renick; F J Floyd; S M Stanley; M Clements
Journal:  J Consult Clin Psychol       Date:  1993-02

5.  New heterosexually transmitted HIV infections in married or cohabiting couples in urban Zambia and Rwanda: an analysis of survey and clinical data.

Authors:  Kristin L Dunkle; Rob Stephenson; Etienne Karita; Elwyn Chomba; Kayitesi Kayitenkore; Cheswa Vwalika; Lauren Greenberg; Susan Allen
Journal:  Lancet       Date:  2008-06-28       Impact factor: 79.321

6.  Are couple-based interventions more effective than interventions delivered to individuals in promoting HIV protective behaviors? A meta-analysis.

Authors:  Nicole Crepaz; Malu V Tungol-Ashmon; H Waverly Vosburgh; Brittney N Baack; Mary M Mullins
Journal:  AIDS Care       Date:  2015-11-25

7.  Implementation of couples' voluntary HIV counseling and testing services in Durban, South Africa.

Authors:  William Kilembe; Kristin M Wall; Mammekwa Mokgoro; Annie Mwaanga; Elisabeth Dissen; Miriam Kamusoko; Hilda Phiri; Jean Sakulanda; Jonathan Davitte; Tarylee Reddy; Mark Brockman; Thumbi Ndung'u; Susan Allen
Journal:  BMC Public Health       Date:  2015-07-02       Impact factor: 3.295

8.  The Impact of Repeat HIV Testing on Risky Sexual Behavior: Evidence from a Randomized Controlled Trial in Malawi.

Authors:  Adeline Delavande; Zachary Wagner; Neeraj Sood
Journal:  J AIDS Clin Res       Date:  2016-03-02

9.  The Role of Relationship Dynamics and Gender Inequalities As Barriers to HIV-Serostatus Disclosure: Qualitative Study among Women and Men Living with HIV in Durban, South Africa.

Authors:  Divya S Bhatia; Abigail D Harrison; Muriel Kubeka; Cecilia Milford; Angela Kaida; Francis Bajunirwe; Ira B Wilson; Christina Psaros; Steven A Safren; David R Bangsberg; Jennifer A Smit; Lynn T Matthews
Journal:  Front Public Health       Date:  2017-07-31

10.  Sexual risk after HIV diagnosis: a comparison of pre-ART individuals with CD4>500 cells/µl and ART-eligible individuals in a HIV treatment and care programme in rural KwaZulu-Natal, South Africa.

Authors:  Nuala McGrath; Linda Richter; Marie-Louise Newell
Journal:  J Int AIDS Soc       Date:  2013-08-05       Impact factor: 5.396

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  19 in total

1.  The Unaddressed Needs of Alcohol-Using Couples on Antiretroviral Therapy in Malawi: Formative Research on Multilevel Interventions.

Authors:  Amy A Conroy; Allison Ruark; Stacey A McKenna; Judy Y Tan; Lynae A Darbes; Judith A Hahn; James Mkandawire
Journal:  AIDS Behav       Date:  2020-06

Review 2.  A Systematic Review of Behavioral Couples-Based Interventions Targeting Prevention of Mother-to-Child Transmission in Low- and Middle-Income Countries.

Authors:  Karen Hampanda; Krysta Pelowich; Benjamin H Chi; Lynae A Darbes; Janet M Turan; Wilbroad Mutale; Lisa Abuogi
Journal:  AIDS Behav       Date:  2021-08-20

3.  Relationship Dynamics are Associated with Self-Reported Adherence but not an Objective Adherence Measure in Malawi.

Authors:  Amy A Conroy; Stacey McKenna; Allison Ruark; Torsten B Neilands; Matthew Spinelli; Monica Gandhi
Journal:  AIDS Behav       Date:  2022-05-04

4.  Protocol for an attention-matched randomized controlled trial of 2GETHER: a relationship education and HIV prevention program for young male couples.

Authors:  Michael E Newcomb; Elissa L Sarno; Emily Bettin; Adam Conway; James Carey; Christopher Garcia; Ricky Hill; Kyle Jozsa; Gregory Swann; Elizabeth L Addington; Jody D Ciolino; Kathryn Macapagal; Judith T Moskowitz; Brian Mustanski; Sarah W Whitton
Journal:  Trials       Date:  2022-06-20       Impact factor: 2.728

5.  Couple Efficacy and Communal Coping for HIV Prevention Among Kenyan Pregnant Couples.

Authors:  Pamela Musoke; Lynae Darbes; Abigail M Hatcher; Anna Helova; Zachary Kwena; George Owino; Elizabeth A Bukusi; Janet M Turan
Journal:  AIDS Behav       Date:  2022-02-05

Review 6.  A Systematic Review of HIV Testing Implementation Strategies in Sub-Saharan African Countries.

Authors:  Ivy Mannoh; Danielle Amundsen; Gnilane Turpin; Carrie E Lyons; Nikita Viswasam; Elizabeth Hahn; Sofia Ryan; Stefan Baral; Bhakti Hansoti
Journal:  AIDS Behav       Date:  2021-11-19

7.  Pathways for HIV Prevention Behaviors Following a Home-Based Couples Intervention for Pregnant Women and Male Partners in Kenya.

Authors:  Abigail M Hatcher; Lynae Darbes; Zachary Kwena; Pamela L Musoke; Anna Joy Rogers; George Owino; Anna Helova; Jami L Anderson; Patrick Oyaro; Elizabeth A Bukusi; Janet M Turan
Journal:  AIDS Behav       Date:  2020-07

8.  Effects of the Waya Intervention on Marital Satisfaction and HIV Risk Behaviors in Western Kenya: A Pre-Post Study Design.

Authors:  Zachary Arochi Kwena; Elizabeth A Bukusi; Janet M Turan; Lynae Darbes; Carey Farquhar; Catherine Makokha; Jared M Baeten
Journal:  Arch Sex Behav       Date:  2022-03-25

9.  Throwing the bones to diagnose HIV: Views of rural South African traditional healers on undertaking HIV counselling and testing.

Authors:  Carolyn M Audet; Elise M Clemens; Sizzy Ngobeni; Mevian Mkansi; Daniel E Sack; Ryan G Wagner
Journal:  AIDS Care       Date:  2020-08-17

10.  Relationship Education and HIV Prevention for Young Male Couples Administered Online via Videoconference: Protocol for a National Randomized Controlled Trial of 2GETHER.

Authors:  Michael E Newcomb; Elissa L Sarno; Emily Bettin; James Carey; Jody D Ciolino; Ricky Hill; Christopher P Garcia; Kathryn Macapagal; Brian Mustanski; Gregory Swann; Sarah W Whitton
Journal:  JMIR Res Protoc       Date:  2020-01-27
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