Literature DB >> 30730320

Rare Manifestation of Gout: Gouty Tophi in the Nose.

Georgi IIliev1, Polina Petrova Ivanova1, Plamen Nedev1, Hristo Popov2.   

Abstract

Gout is a disease characterized by abnormal metabolism of the uric acid, leading to undesired buildup of monosodium urate crystals affecting mainly the first metatarsal-phalangeal joint of the foot and less commonly other joints or the soft tissues of the body. The prevalence of the disease increases with age, and it is statistically more observed in men than in women.We present the case of a 62-year-old male patient diagnosed as having gout 20 years ago. He came to the clinic with a nasal hump and a mass growing in his nose for the last 3 years, presenting as a nasal obstruction and facial deformity. Although the patient was treated with allopurinol and nonsteroidal anti-inflammatory drugs, surgical treatment was deemed necessary, and the patient was taken to receive a surgical resection of the nasal mass. The follow-up histopathology observation revealed deposits of urate crystals surrounded by a granulomatous inflammation. This confirmed the diagnosis-gouty tophi in the nose. In the follow-up period after the surgery, the patient reported overall improved breathing and aesthetic results.Tophi can be found in atypical locations, which increases morbidities and deformities caused by the disease. We report on this peculiar case of tophaceus gout as it is-a rare manifestation of the disease with tophi located in the nasal region.

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Year:  2019        PMID: 30730320     DOI: 10.1097/SAP.0000000000001778

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  1 in total

Review 1.  Beyond Medical Treatment: Surgical Treatment of Gout.

Authors:  Jonathan Carcione; Shari Bodofsky; Brian LaMoreaux; Naomi Schlesinger
Journal:  Curr Rheumatol Rep       Date:  2020-11-24       Impact factor: 4.592

  1 in total

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