Literature DB >> 3072883

Firefly luciferase as a tool in molecular and cell biology.

S J Gould1, S Subramani.   

Abstract

The unique properties of firefly luciferase and the cloning of the gene for this enzyme have spawned a number of novel applications of this protein. We summarize a few of these applications including its use as a reporter gene, as a model for the study of protein import into peroxisomes, and as a component of a heterologous gene expression system.

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Year:  1988        PMID： 3072883     DOI： 10.1016/0003-2697(88)90353-3

Source DB:  PubMed          Journal:  Anal Biochem        ISSN： 0003-2697            Impact factor:   3.365


  57 in total

1.  MR-based molecular imaging of the brain: the next frontier.

Authors:  M E de Backer; R J A Nabuurs; M A van Buchem; L van der Weerd
Journal:  AJNR Am J Neuroradiol       Date:  2010-09-23       Impact factor: 3.825

2.  Firefly luciferase can use L-luciferin to produce light.

Authors:  N Lembert
Journal:  Biochem J       Date:  1996-07-01       Impact factor: 3.857

3.  Use of Leishmania donovani field isolates expressing the luciferase reporter gene in in vitro drug screening.

Authors:  Suman Gupta; Shyam Sundar; Neena Goyal
Journal:  Antimicrob Agents Chemother       Date:  2005-09       Impact factor: 5.191

Review 4.  Unraveling the secret lives of bacteria: use of in vivo expression technology and differential fluorescence induction promoter traps as tools for exploring niche-specific gene expression.

Authors:  Hans Rediers; Paul B Rainey; Jos Vanderleyden; René De Mot
Journal:  Microbiol Mol Biol Rev       Date:  2005-06       Impact factor: 11.056

5.  Adaptation of a luciferase gene reporter and lac expression system to Borrelia burgdorferi.

Authors:  Jon S Blevins; Andrew T Revel; Alexandra H Smith; Gulnaz N Bachlani; Michael V Norgard
Journal:  Appl Environ Microbiol       Date:  2007-01-12       Impact factor: 4.792

6.  Molecular motor-induced instabilities and cross linkers determine biopolymer organization.

Authors:  D Smith; F Ziebert; D Humphrey; C Duggan; M Steinbeck; W Zimmermann; J Käs
Journal:  Biophys J       Date:  2007-06-29       Impact factor: 4.033

7.  A reporter gene imaging system for monitoring microRNA biogenesis.

Authors:  Hae Young Ko; Do Won Hwang; Dong Soo Lee; Soonhag Kim
Journal:  Nat Protoc       Date:  2009-10-29       Impact factor: 13.491

8.  A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor.

Authors:  S B Vande Pol; P M Howley
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

9.  Molecular prioritization strategies to identify functional genetic variants in the cardiovascular disease-associated expression QTL Vanin-1.

Authors:  Belinda J Kaskow; Luke A Diepeveen; J Michael Proffitt; Alexander J Rea; Daniela Ulgiati; John Blangero; Eric K Moses; Lawrence J Abraham
Journal:  Eur J Hum Genet       Date:  2013-09-18       Impact factor: 4.246

10.  Luciferase activity as a marker of tumor burden and as an indicator of tumor response to antineoplastic therapy in vivo.

Authors:  L Zhang; K E Hellström; L Chen
Journal:  Clin Exp Metastasis       Date:  1994-03       Impact factor: 5.150
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