Literature DB >> 30728706

Effect of Intrasocket Application of Manuka Honey on Postsurgical Pain of Impacted Mandibular Third Molars Surgery: Split-Mouth Randomized Controlled Trial.

Nuraldeen M Al-Khanati1, Yasser Al-Moudallal1.   

Abstract

BACKGROUND AND
PURPOSE: Sufficient evidence exists recommending the use of honey in the management of wounds. Studies revealed that the healing effect of honey could be classified by its antibacterial and anti-inflammatory properties of its components. Since surgical extraction of impacted molars is one of the most common operations in the oral cavity and the postoperative pain disturbing the patient may reduce the quality of health service, this study aimed to assess the analgesic potential of Manuka honey application into the extraction socket of impacted mandibular third molars.
METHODS: This randomized split-mouth controlled study included 33 patients undergoing impacted bilateral lower third molars surgery under local anesthesia (n = 66). Randomization was carried out by coin flipping. One of the two impacted third molars was assigned to treatment group (Manuka honey applied just before suturing), other side to control group (nothing applied). Postsurgical pain was evaluated using visual analogue scale (VAS) of faces 7 days after extraction. The total analgesic dose used was also evaluated.
RESULTS: In treatment group, postoperative VAS scores were significantly lower compared to that in control group regarding first and second days postoperatively (P < 0.05). Total analgesic intake in the control group was significantly higher (P = 0.0001).
CONCLUSION: This study demonstrated that intrasocket application of Manuka honey after surgical extraction of impacted lower third molar is an effective method for reducing acute postsurgical pain.

Entities:  

Keywords:  Impaction; Manuka honey; Pain; Postoperative analgesia; Third molar surgery

Year:  2018        PMID: 30728706      PMCID: PMC6328820          DOI: 10.1007/s12663-018-1142-z

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  23 in total

Review 1.  The role of honey in the management of wounds.

Authors:  P C Molan
Journal:  J Wound Care       Date:  1999-09       Impact factor: 2.072

2.  A 5.8-kDa component of manuka honey stimulates immune cells via TLR4.

Authors:  A J Tonks; E Dudley; N G Porter; J Parton; J Brazier; E L Smith; A Tonks
Journal:  J Leukoc Biol       Date:  2007-08-03       Impact factor: 4.962

Review 3.  Clinical usage of honey as a wound dressing: an update.

Authors:  P C Molan; J A Betts
Journal:  J Wound Care       Date:  2004-10       Impact factor: 2.072

Review 4.  Influence of pH on wound-healing: a new perspective for wound-therapy?

Authors:  Lars Alexander Schneider; Andreas Korber; Stephan Grabbe; Joachim Dissemond
Journal:  Arch Dermatol Res       Date:  2006-11-08       Impact factor: 3.017

Review 5.  Honey: nutritional and medicinal value.

Authors:  F R Khan; Z Ul Abadin; N Rauf
Journal:  Int J Clin Pract       Date:  2007-10       Impact factor: 2.503

Review 6.  Honey in the treatment of burns: a systematic review and meta-analysis of its efficacy.

Authors:  Meme Wijesinghe; Mark Weatherall; Kyle Perrin; Richard Beasley
Journal:  N Z Med J       Date:  2009-05-22

Review 7.  Honey for wound healing, ulcers, and burns; data supporting its use in clinical practice.

Authors:  Noori Al-Waili; Khelod Salom; Ahmad A Al-Ghamdi
Journal:  ScientificWorldJournal       Date:  2011-04-05

8.  Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand.

Authors:  Elvira Mavric; Silvia Wittmann; Gerold Barth; Thomas Henle
Journal:  Mol Nutr Food Res       Date:  2008-04       Impact factor: 5.914

Review 9.  Systematic review of the use of honey as a wound dressing.

Authors:  O A Moore; L A Smith; F Campbell; K Seers; H J McQuay; R A Moore
Journal:  BMC Complement Altern Med       Date:  2001-06-04       Impact factor: 3.659

10.  Medical honey for wound care--still the 'latest resort'?

Authors:  Arne Simon; Kirsten Traynor; Kai Santos; Gisela Blaser; Udo Bode; Peter Molan
Journal:  Evid Based Complement Alternat Med       Date:  2008-01-07       Impact factor: 2.629

View more
  3 in total

1.  A novel therapeutic approach for reducing postoperative inflammatory complications after impacted mandibular third molar removal.

Authors:  Alaa Abdelqader Altaweel; Abd El-Hamid Gaber; Mahmoud Z Alnaffar; Abdulrahman S Almowallad; Mohamad H Almech; Abeer S Almuwallad; Rawan K Alharbi; Wasan A Arab
Journal:  Medicine (Baltimore)       Date:  2022-09-16       Impact factor: 1.817

2.  The influence of intra-alveolar application of honey versus Chlorhexidine rinse on the incidence of Alveolar Osteitis following molar teeth extraction. A randomized clinical parallel trial.

Authors:  Nedal Abu-Mostafa; Saja Al-Daghamin; Asma Al-Anazi; Nesreen Al-Jumaah; Amenah Alnesafi
Journal:  J Clin Exp Dent       Date:  2019-10-01

3.  Systemic Use of Arnica Montana for the Reduction of Postsurgical Sequels following Extraction of Impacted Mandibular 3rd Molars: A Pilot Study.

Authors:  Hani Mawardi; Shaima Ghazalh; Ahmad Shehatah; Amnah Abdelwahid; Amin Aljohani; Osama Felemban; Soulafa Almazrooa; Lena Elbadawi; Hazem Shawky
Journal:  Evid Based Complement Alternat Med       Date:  2020-12-12       Impact factor: 2.629

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.