Literature DB >> 30728700

Comparison of Local Anaesthetic Efficacy of Tramadol Versus Lignocaine for Extraction of Tooth Under Supraperiosteal Infiltration.

Shoeb Kasim Jendi1, Ahmed M Syed2, Sheeraz Badal2, Amol Doiphode2, Sandesh S Chougule2, Sameer A Shaikh2, Ahmed Ahtesham2.   

Abstract

BACKGROUND: Tramadol has been shown to have a local anaesthetic effect when used as infiltration anaesthesia.
METHODS: The local anaesthetic efficacy of tramadol was compared with that of lignocaine for the extraction of teeth in terms of their onset of action, duration of action, intraoperative pain, post-operative analgesic effect and adverse reactions. Apart from this, incidence of allergic reaction was also recorded for both the drugs. A total of 100 patients were divided into two groups randomly. Each patient was assigned to receive either a maximum of 2 ml of 5% tramadol (Supridol 50 mg, Neon laboratories), Group T (n = 50), as a local anaesthetic solution for extraction of maxillary premolar for orthodontic reason under supraperiosteal infiltration following strict aseptic precaution or a maximum of 2 ml of 2% lignocaine (Lox 2%, Neon laboratories), Group L (n = 50), in a double-blinded fashion.
RESULTS: In group T, the mean subjective onset of action was 33.66 s, while in group L it was 33.06 s (p = 0.881). In group T, the mean objective onset of action was 3.04 min, while in group L it was 3.18 min (p > 0.05). The mean duration of action in group T was 55.60 min, while in group L it was 57.50 min (p = 0.432). Only 2 patients in group T and 1 patient in group L had nausea (p = 0.245).
CONCLUSION: We conclude that 5% tramadol has a local anaesthetic efficacy similar to 2% lignocaine but is comparatively a weaker agent.

Entities:  

Keywords:  Lignocaine; Local anaesthesia; Supraperiosteal infiltration; Tramadol

Year:  2018        PMID: 30728700      PMCID: PMC6328823          DOI: 10.1007/s12663-018-1104-5

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  20 in total

1.  Comparison of nerve conduction blocks by an opioid and a local anesthetic.

Authors:  Tufan Mert; Yasemin Gunes; Mustafa Guven; Ismail Gunay; Dilek Ozcengiz
Journal:  Eur J Pharmacol       Date:  2002-03-29       Impact factor: 4.432

2.  Tonic blocking action of meperidine on Na+ and K+ channels in amphibian peripheral nerves.

Authors:  M E Bräu; E D Koch; W Vogel; G Hempelmann
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3.  Comparative effects of lidocaine and tramadol on injured peripheral nerves.

Authors:  Tufan Mert; Yasemin Gunes; Dilek Ozcengiz; Ismail Gunay; Sait Polat
Journal:  Eur J Pharmacol       Date:  2006-06-10       Impact factor: 4.432

4.  Direct tramadol application on sciatic nerve inhibits spinal somatosensory evoked potentials in rats.

Authors:  Y C Tsai; P J Chang; I M Jou
Journal:  Anesth Analg       Date:  2001-06       Impact factor: 5.108

5.  Effects of tramadol on nerve action potentials in rat: comparisons with benzocaine and lidocaine.

Authors:  Mustafa Güven; Tufan Mert; Ismail Günay
Journal:  Int J Neurosci       Date:  2005-03       Impact factor: 2.292

6.  The peripheral analgesic effect of tramadol in reducing propofol injection pain: a comparison with lidocaine.

Authors:  W W Pang; P Y Huang; D P Chang; M H Huang
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Review 7.  Clinical pharmacology of tramadol.

Authors:  Stefan Grond; Armin Sablotzki
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

8.  The postoperative analgesic effect of tramadol when used as subcutaneous local anesthetic.

Authors:  Hanife Altunkaya; Yetkin Ozer; Eksal Kargi; Isil Ozkocak; Mübin Hosnuter; Cengiz Bekir Demirel; Orhan Babuccu
Journal:  Anesth Analg       Date:  2004-11       Impact factor: 5.108

Review 9.  Tramadol: a review of its use in perioperative pain.

Authors:  L J Scott; C M Perry
Journal:  Drugs       Date:  2000-07       Impact factor: 9.546

10.  Comparison of local anaesthetic effects of tramadol with prilocaine for minor surgical procedures.

Authors:  H Altunkaya; Y Ozer; E Kargi; O Babuccu
Journal:  Br J Anaesth       Date:  2003-03       Impact factor: 9.166

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  3 in total

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Authors:  Maria Beatrice Passavanti; Giacomo Piccinno; Aniello Alfieri; Sveva Di Franco; Pasquale Sansone; Giuseppe Mangoni; Vincenzo Pota; Caterina Aurilio; Maria Caterina Pace; Marco Fiore
Journal:  Syst Rev       Date:  2020-07-13

Review 2.  Tramadol as a local anaesthetic agent in dentistry: A systematic review of local and systemic adverse effects.

Authors:  Robert Jonathon Mane; Joanne Jung Eun Choi; William Fox Sharpe-Davidson
Journal:  Saudi Dent J       Date:  2021-09-13

3.  Effectiveness of tramadol compared to lignocaine as local anesthesia in the extraction of firm teeth: a randomized controlled trial.

Authors:  Manu Goel; Pinaki Sen; Tushar Maturkar; Siddhesh Latke; Tejasvini Dehankar
Journal:  J Dent Anesth Pain Med       Date:  2021-06-01
  3 in total

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