Literature DB >> 307275

Isolated retinas synthesize visual pigments from tetinol congeners delivered by liposomes.

S Uoshikami, G N Nöll.   

Abstract

Isolated vertebrate retinas bathed in circulating Ringer solution cannot regenerate all of their bleached visual pigments. When dioleoyl-lecithin vesicles containing certain retinol congeners are added to the Ringer solution, such retinas begin to regenerate pigment immediately. The visual pigment of a bleached perfused retina can now be restored fully, making the isolated retina an independent unit for study. Loposomes can protect oxygen-sensitive, lipid-soluble substances and deliver them to living cells.

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Year:  1978        PMID： 307275     DOI： 10.1126/science.307275

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  Sensitization of bleached rod photoreceptors by 11-cis-locked analogues of retinal.

Authors:  D W Corson; M C Cornwall; E F MacNichol; J Jin; R Johnson; F Derguini; R K Crouch; K Nakanishi
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

2.  Bleached pigment activates transduction in isolated rods of the salamander retina.

Authors:  M C Cornwall; G L Fain
Journal:  J Physiol       Date:  1994-10-15       Impact factor: 5.182

3.  Photoreceptor differentiation in cerebellar medulloblastoma: evidence for a functional photopigment and authentic S-antigen (arrestin).

Authors:  C M Kramm; H W Korf; M Czerwionka; W Schachenmayr; W J de Grip
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

4.  Membrane specializations in the peripheral retina of the housefly Musca domestica L.

Authors:  C Chi; D Carlson; R L St Marie
Journal:  Cell Tissue Res       Date:  1979-05-25       Impact factor: 5.249

5.  Retinoid requirements for recovery of sensitivity after visual-pigment bleaching in isolated photoreceptors.

Authors:  G J Jones; R K Crouch; B Wiggert; M C Cornwall; G J Chader
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

Review 6.  Interphotoreceptor retinoid-binding protein (IRBP). Molecular biology and physiological role in the visual cycle of rhodopsin.

Authors:  D R Pepperberg; T L Okajima; B Wiggert; H Ripps; R K Crouch; G J Chader
Journal:  Mol Neurobiol       Date:  1993       Impact factor: 5.590

7.  On the evaluation of photoreceptor properties by micro-fluorimetric measurements of fluorochrome diffusion.

Authors:  P Hochstrate; H Rüppel
Journal:  Biophys Struct Mech       Date:  1980

8.  Rod-opsin immunoreaction in the pineal organ of the pigmented mouse does not indicate the presence of a functional photopigment.

Authors:  C M Kramm; W J de Grip; H W Korf
Journal:  Cell Tissue Res       Date:  1993-10       Impact factor: 5.249

9.  Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells.

Authors:  D M Mihai; I Washington
Journal:  Cell Death Dis       Date:  2014-07-24       Impact factor: 8.469
  9 in total

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