Sumit Mukherjee1, Sukhen Das Mandal2, Nikita Gupta3, Matan Drory-Retwitzer4, Danny Barash4, Supratim Sengupta1. 1. Department of Physical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur-741246, India. 2. Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur-741246, India. 3. Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (BHU) Varanasi, Varanasi, India. 4. Department of Computer Science, Ben-Gurion University, Beer-Sheva, Israel.
Abstract
SUMMARY: Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea. AVAILABILITY AND IMPLEMENTATION: RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.
SUMMARY: Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea. AVAILABILITY AND IMPLEMENTATION: RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.
Authors: Olga M Sokolovskaya; Kenny C Mok; Jong Duk Park; Jennifer L A Tran; Kathryn A Quanstrom; Michiko E Taga Journal: mBio Date: 2019-09-24 Impact factor: 7.867