Literature DB >> 30725422

L-[Methyl-11C] Methionine-Positron-Emission Tomography (MET-PET).

Robert M Hoffman1,2.   

Abstract

Methionine (MET) dependence is a cancer-specific metabolic abnormality that is due to MET overuse for aberrant transmethylation reactions. [11C]-MET is very useful for positron-emission tomography (PET) due to MET overuse in malignant tumors. Many benefits of MET-PET have been demonstrated. MET-PET can differentiate recurrent glioma and necrosis. [11C]-MET-PET can also predict prognosis in gliomas better than [18F]-FDG PET. [11C]-MET-PET is better than MRI for predicting survival in low-grade glioma (LGG). MET-PET has greater specificity for detecting residual tumor after surgery than MRI.

Entities:  

Keywords:  Cancer; Hoffman effect; MET-PET; Methionine dependence; Methoinine uptake; PET imaging; Positron-emission tomography; Transmethylation; [11C]-MET

Mesh：

Substances：

Year:  2019        PMID： 30725422     DOI： 10.1007/978-1-4939-8796-2_20

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  3 in total

1.  Lymph Nodes Draining Infections Investigated by PET and Immunohistochemistry in a Juvenile Porcine Model.

Authors:  Pia Afzelius; Malene Kjelin Morsing; Ole Lerberg Nielsen; Aage Kristian Olsen Alstrup; Svend Borup Jensen; Lars Jødal
Journal:  Molecules       Date:  2022-04-27       Impact factor: 4.927

2.  IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein-specific PET/CT.

Authors:  Manuel Röhrich; Anastasia Loktev; Annika K Wefers; Annette Altmann; Daniel Paech; Sebastian Adeberg; Paul Windisch; Thomas Hielscher; Paul Flechsig; Ralf Floca; Dominik Leitz; Julius P Schuster; Peter E Huber; Jürgen Debus; Andreas von Deimling; Thomas Lindner; Uwe Haberkorn
Journal:  Eur J Nucl Med Mol Imaging       Date:  2019-08-06       Impact factor: 9.236

3.  Sarcoidosis-lymphoma syndrome with portal hypertension: diagnostic clues and approach.

Authors:  Fumio Chikamori; Kenji Yorita; Tadashi Yoshino; Satoshi Ito; Miki Mizobuchi; Koji Ueta; Kai Mizobuchi; Shigeto Shimizu; Kazumasa Nanjo; Sawaka Yukishige; Jun Iwabu; Hisashi Matsuoka; Norihiro Hokimoto; Hiromichi Yamai; Kazuhisa Onishi; Nobuyuki Tanida; Niranjan Sharma
Journal:  Radiol Case Rep       Date:  2021-06-12
  3 in total

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