Literature DB >> 30724834

HIV-1 Drug Resistance and Virologic Outcomes Among Tanzanian Youth Living With HIV.

Dorothy E Dow1,2,3, Aisa M Shayo2, Coleen K Cunningham1,3, Blandina T Mmbaga2,3,4.   

Abstract

Adolescents living with HIV tend to have poor adherence that often breeds HIV resistance mutations and virologic failure (VF). This study evaluated risk behavior, virologic outcomes and HIV resistance mutations in Tanzanian youth living with HIV. Participants were primarily perinatally infected and of mean age 16.7 years; among them 41.5% had VF. Those receiving first-line therapy demonstrated over 90% resistance to their current therapy.

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Year:  2019        PMID： 30724834      PMCID： PMC6857177          DOI： 10.1097/INF.0000000000002288

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  12 in total

1.  Antiretroviral drug concentrations in hair are associated with virologic outcomes among young people living with HIV in Tanzania.

Authors:  Zachary J Tabb; Blandina T Mmbaga; Monica Gandhi; Alexander Louie; Karen Kuncze; Hideaki Okochi; Aisa M Shayo; Elizabeth L Turner; Coleen K Cunningham; Dorothy E Dow
Journal:  AIDS       Date:  2018-06-01       Impact factor: 4.177

2.  Prevention of HIV-1 infection with early antiretroviral therapy.

Authors:  Myron S Cohen; Ying Q Chen; Marybeth McCauley; Theresa Gamble; Mina C Hosseinipour; Nagalingeswaran Kumarasamy; James G Hakim; Johnstone Kumwenda; Beatriz Grinsztejn; Jose H S Pilotto; Sheela V Godbole; Sanjay Mehendale; Suwat Chariyalertsak; Breno R Santos; Kenneth H Mayer; Irving F Hoffman; Susan H Eshleman; Estelle Piwowar-Manning; Lei Wang; Joseph Makhema; Lisa A Mills; Guy de Bruyn; Ian Sanne; Joseph Eron; Joel Gallant; Diane Havlir; Susan Swindells; Heather Ribaudo; Vanessa Elharrar; David Burns; Taha E Taha; Karin Nielsen-Saines; David Celentano; Max Essex; Thomas R Fleming
Journal:  N Engl J Med       Date:  2011-07-18       Impact factor: 91.245

3.  Modality of Primary HIV Disclosure and Association with Mental Health, Stigma, and Antiretroviral Therapy Adherence in Tanzanian Youth Living with HIV.

Authors:  Julia V Ramos; Blandina T Mmbaga; Elizabeth L Turner; Leonia L Rugalabamu; Severa Luhanga; Coleen K Cunningham; Dorothy E Dow
Journal:  AIDS Patient Care STDS       Date:  2018-01       Impact factor: 5.078

4.  HIV Resistance and Prevention of Mother-to-Child Transmission Regimen in HIV-Infected Infants in Northern Tanzania.

Authors:  Dorothy E Dow; Werner Schimana; Balthazar M Nyombi; Blandina T Mmbaga; Aisa M Shayo; John A Bartlett; Charles G Massambu; Emmanuel G Kifaro; Elizabeth L Turner; Todd DeMarco; Fangping Cai; Coleen K Cunningham; Ann M Buchanan
Journal:  AIDS Res Hum Retroviruses       Date:  2017-10-05       Impact factor: 2.205

5.  Emergence of untreatable, multidrug-resistant HIV-1 in patients failing second-line therapy in Kenya.

Authors:  Seth C Inzaule; Raph L Hamers; Irene Mukui; Kennedy Were; Prestone Owiti; Daniel Kwaro; Tobias F Rinke de Wit; Clement Zeh
Journal:  AIDS       Date:  2017-06-19       Impact factor: 4.177

6.  Web resources for HIV type 1 genotypic-resistance test interpretation.

Authors:  Tommy F Liu; Robert W Shafer
Journal:  Clin Infect Dis       Date:  2006-04-28       Impact factor: 9.079

7.  Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa.

Authors:  Jean B Nachega; Michael Hislop; Hoang Nguyen; David W Dowdy; Richard E Chaisson; Leon Regensberg; Mark Cotton; Gary Maartens
Journal:  J Acquir Immune Defic Syndr       Date:  2009-05-01       Impact factor: 3.731

8.  Evaluating mental health difficulties and associated outcomes among HIV-positive adolescents in Tanzania.

Authors:  Dorothy E Dow; Elizabeth L Turner; Aisa M Shayo; Blandina Mmbaga; Coleen K Cunningham; Karen O'Donnell
Journal:  AIDS Care       Date:  2016-02-03

9.  Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV-infected children in Tanzania: a four-year follow-up.

Authors:  Dorothy E Dow; Aisa M Shayo; Coleen K Cunningham; Elizabeth A Reddy
Journal:  BMC Infect Dis       Date:  2014-11-07       Impact factor: 3.090

10.  Impact of HIV Drug Resistance on HIV/AIDS-Associated Mortality, New Infections, and Antiretroviral Therapy Program Costs in Sub-Saharan Africa.

Authors:  Andrew N Phillips; John Stover; Valentina Cambiano; Fumiyo Nakagawa; Michael R Jordan; Deenan Pillay; Meg Doherty; Paul Revill; Silvia Bertagnolio
Journal:  J Infect Dis       Date:  2017-05-01       Impact factor: 5.226
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  4 in total

1.  "We give them threatening advice…": expectations of adherence to antiretroviral therapy and their consequences among adolescents living with HIV in rural Malawi.

Authors:  Rose Burns; Denview Magalasi; Philippe Blasco; Elisabeth Szumilin; Estelle Pasquier; Birgit Schramm; Alison Wringe
Journal:  J Int AIDS Soc       Date:  2020-03       Impact factor: 5.396

2.  Adherence challenges and opportunities for optimizing care through enhanced adherence counseling for adolescents with suspected HIV treatment failure in Kenya.

Authors:  Michelle M Gill; James N Ndimbii; Rose Otieno-Masaba; Millicent Ouma; Stella Jabuto; Boniface Ochanda
Journal:  BMC Health Serv Res       Date:  2022-07-29       Impact factor: 2.908

3.  A group-based mental health intervention for young people living with HIV in Tanzania: results of a pilot individually randomized group treatment trial.

Authors:  Dorothy E Dow; Blandina T Mmbaga; John A Gallis; Elizabeth L Turner; Monica Gandhi; Coleen K Cunningham; Karen E O'Donnell
Journal:  BMC Public Health       Date:  2020-09-04       Impact factor: 4.135

4.  Challenges and facilitators of transition from adolescent to adult HIV care among young adults living with HIV in Moshi, Tanzania.

Authors:  Rita V Masese; Julia V Ramos; Leonia Rugalabamu; Severa Luhanga; Aisa M Shayo; Kearsley A Stewart; Coleen K Cunningham; Dorothy E Dow
Journal:  J Int AIDS Soc       Date:  2019-10       Impact factor: 5.396
  4 in total

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