Literature DB >> 30720847

The pattern of risk-factor profile in Egyptian patients with acute coronary syndrome: phase II of the Egyptian cross-sectional CardioRisk project.

Ashraf Reda1, Mohamed Ashraf2, Mahmoud Soliman3, Hany Ragy2, Ahmed El Kersh3, Waleed Abdou2, Tamer Mostafa4, Mohammed Hassan5, Elsayed Farag4, Hazem Khamis6, Moheb Wadie7, Atef Elbahry8, Sameh Salama5, Ghada Kazamel2, Mohammed Sadaka9, Morsy Mostafa3, Akram Abd El-Bary10, Osama Sanad11, Samir Rafla9, Yaser Abd El-Hady12, Mohammed Selim2, Nabil Farag13, Helmy El-Ghawaby12, Hosam El-Araby14, Sameh Emil15, Morad Beshay3, Ahmed Shawky13, Mahmoud Yusef7, Mohammed Abd El-Ghany5, Awni Gamal3, Yaser Baghdady5, Taymour Mostafa16, Mohammed Zahran13, Khaled El Rabat11, Ahmed Bendary11, Amany El Shorbagy17.   

Abstract

BACKGROUND: Egypt is the most populous country in the Middle East and North Africa and has more than 15% of the cardiovascular deaths in the region, but little is known about the prevalence of traditional risk factors and treatment strategies in acute coronary syndrome (ACS) patients across Egypt.
METHODS: From November 2015 to August 2017, data were collected from 1 681 patients with ACS in 30 coronary care centres, covering 11 governorates across Egypt, spanning the Mediterranean coast, Nile Delta and Upper Egypt, with a focus on risk factors and management strategies.
RESULTS: Women constituted 25% of the patients. Premature ACS was common, with 43% of men aged less than 55 years, and 67% of women under 65 years. Most men had ST-elevation myocardial infarction (STEMI) (49%), while a larger percentage of women had unstable angina and non-ST-elevation myocardial infarction (NSTEMI) (32% each; p < 0.001). Central obesity was present in 80% of men and 89% of women, with 32% of men and women having atherogenic dyslipidaemia. Current smoking was reported by 62% of men and by 72% of men under 55 years. A larger proportion of women had type 2 diabetes (53 vs 34% of men), hypertension (69 vs 49%), dyslipidaemia, and obesity (71 vs 41%) (p < 0.001 for all). There were no gender differences in most diagnostic and therapeutic procedures, but among STEMI patients, 51% of men underwent primary percutaneous coronary intervention compared to 46% of women (p = 0.064).
CONCLUSIONS: Central obesity and smoking are extremely prevalent in Egypt, contributing to an increased burden of premature ACS, which warrants tailored prevention strategies. The recognised tendency worldwide to treat men more aggressively was less pronounced than expected.

Entities:  

Keywords:  Egypt; acute coronary syndrome; risk factors

Mesh:

Substances:

Year:  2019        PMID: 30720847     DOI: 10.5830/CVJA-2018-074

Source DB:  PubMed          Journal:  Cardiovasc J Afr        ISSN: 1015-9657            Impact factor:   1.167


  10 in total

1.  Egyptian Association of Vascular Biology and Atherosclerosis (EAVA) consensus on the usage of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.

Authors:  Ashraf Reda; Ahmed Shawky Elserafy; Elsayed Farag; Tamer Mostafa; Nabil Farag; Atef Elbahry; Osama Sanad; Ahmed Bendary; Ahmed Elkersh; Mohammed Selim; Morad Beshay; Hazem Khamis
Journal:  Egypt Heart J       Date:  2020-05-18

2.  Association between age and infection in patients with acute ST-elevation myocardial infarction.

Authors:  Magdy Algowhary
Journal:  Egypt Heart J       Date:  2021-01-30

3.  Effect of CYP2C19 genetic polymorphism on the pharmacodynamics and clinical outcomes for patients treated with ticagrelor: a systematic review with qualitative and quantitative meta-analysis.

Authors:  Qiufen Xie; Qian Xiang; Zhiyan Liu; Guangyan Mu; Shuang Zhou; Zhuo Zhang; Lingyue Ma; Yanjun Gong; Jie Jiang; Yimin Cui
Journal:  BMC Cardiovasc Disord       Date:  2022-03-17       Impact factor: 2.298

Review 4.  A semi-systematic review on hypertension and dyslipidemia care in Egypt-highlighting evidence gaps and recommendations for better patient outcomes.

Authors:  Ashraf Reda; Hany Ragy; Kanwal Saeed; Mohammed Ashraf Alhussaini
Journal:  J Egypt Public Health Assoc       Date:  2021-12-01

5.  Registry for Acute Coronary Events in Nigeria (RACE-Nigeria): Clinical Characterization, Management, and Outcome.

Authors:  Simeon Isezuo; Mahmoud Umar Sani; Abdullahi Talle; Adeyemi Johnson; Abiodun-Moshood Adeoye; Mehmet S Ulgen; Amam Mbakwem; Okechukwu Ogah; Emmanuel Edafe; Philip Kolo; Murtala Nagabea; Rasaaq Adebayo; Eze Nwafor; Folasade Daniel; Muiyawa Zagga; Hayatu Umar; Isa Oboirien; Balarabe A Sulaiman; Umar Abdullahi; Muhammad Sani Mijinyawa; Farouk Buba; Akinyemi Aje; Henry Okolie; Muhammad Nazir Shehu; Umar Adamu; Akinsanya Olusegun-Joseph; Ranti Familoni; Nwuriku Chibuzor; Taiwo Olabisi Olunuga; Emmanuel Ejim; Awodu Rasheed Olaide; Dike Ojji; Bushra Sanni; Jane N Ajuluchukwu; Michael O Balogun; Ayodele B Omotoso; Mullasari Ajit; Ayodele O Falase
Journal:  J Am Heart Assoc       Date:  2021-12-22       Impact factor: 6.106

Review 6.  Sex Differences in Acute Coronary Syndromes: A Global Perspective.

Authors:  F Aaysha Cader; Shrilla Banerjee; Martha Gulati
Journal:  J Cardiovasc Dev Dis       Date:  2022-07-27

7.  A Narrative Review and Expert Panel Recommendations on Dyslipidaemia Management After Acute Coronary Syndrome in Countries Outside Western Europe and North America.

Authors:  Ashraf Reda; Wael Almahmeed; Idit Dobrecky-Mery; Po-Hsun Huang; Ursulo Juarez-Herrera; Naresh Ranjith; Tobias Sayre; Miguel Urina-Triana
Journal:  Adv Ther       Date:  2020-03-29       Impact factor: 3.845

8.  Door-to-balloon time in the treatment of ST segment elevation myocardial infarction in a tertiary care center in Saudi Arabia.

Authors:  Taimur Salar Butt; Eyad Bashtawi; Badis Bououn; Bhawoodin Wagley; Bandar Albarrak; Hani El Sergani; Salman Ibn Mujtaba; Jehad Buraiki
Journal:  Ann Saudi Med       Date:  2020-08-06       Impact factor: 1.526

9.  Prevalence of atherosclerosis risk factors in Egyptian patients with acute coronary syndrome: final data of the nationwide cross-sectional 'CardioRisk' project.

Authors:  Ashraf Reda; Ahmed Bendary; Atef Elbahry; Elsayed Farag; Tamer Mostafa; Hazem Khamis; Moheb Wadie; Mohamed Bendary; Bassant Abdoul Azeem; Rehab Salah
Journal:  J Public Health Afr       Date:  2021-02-11

Review 10.  Egyptian practical guidance in lipid management 2020.

Authors:  Hesham Salah El Din Taha; Hala Mahfouz Badran; Hossam Kandil; Nabil Farag; Abbas Oraby; Magdy El Sharkawy; Khaled Shokry; Fouad Fawzy; Hossam Mahrous; Juliette Bahgat; Mina Samy; Mirna Mamdouh Shaker
Journal:  Egypt Heart J       Date:  2021-02-23
  10 in total

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