Literature DB >> 30719555

Pathology Evaluation of Reduction Mammaplasty Specimens and Subsequent Diagnosis of Malignant Breast Disease: A Claims-Based Analysis.

Erika D Sears1,2,3, Yu-Ting Lu4, Ting-Ting Chung5, Adeyiza O Momoh4, Kevin C Chung4,6.   

Abstract

BACKGROUND: This study aimed to measure the use of pathology evaluation of breast specimens among patients undergoing reduction mammaplasty and assess rates of new diagnoses of breast disease and associated cost.
METHODS: We analyzed the Truven MarketScan Databases from 2009 to 2015 to identify adult female patients undergoing reduction mammaplasty for macromastia. We recorded patient age, rates of obtaining pathology evaluation, new diagnoses of benign or malignant breast disease after pathology evaluation, and total cost for the surgery encounter.
RESULTS: Among 17,738 macromastia patients undergoing reduction mammaplasty, 91.3% (n = 16,193) received pathology evaluation. Pathology evaluation rates were clinically similar across age groups <70 years (90.8-92.1%) and slightly lower for patients ≥70 (85.0%). Among 6987 patients less than 40 years who received pathology evaluation, 0.06% (n = 4) were subsequently diagnosed with malignant breast disease within 3 months, compared to 0.23% in the entire cohort (n = 37/16,193). Pathology claims resulted in an added $307 (SD 251) on average for the breast reduction surgery encounters.
CONCLUSIONS: Breast tissue after reduction mammaplasty is routinely submitted for pathology evaluation, without consideration of age-based risk for breast cancer. Routine pathology evaluation of breast tissue in patients in lower risk age groups (less than 40 years) required an additional $536,000 on average to detect a single occult breast cancer compared to an added $85,600 to detect a new malignancy in patients 40 years and older. Clinicians and policy makers should consider whether routine pathology evaluation of breast tissue should be individualized based on risk factors for breast cancer.

Entities:  

Mesh:

Year:  2019        PMID: 30719555      PMCID: PMC7422755          DOI: 10.1007/s00268-019-04931-1

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  32 in total

1.  Cost and effectiveness of routine pathological examination of operative specimens obtained during primary total hip and knee replacement in patients with osteoarthritis.

Authors:  M S Kocher; G Erens; T S Thornhill; J E Ready
Journal:  J Bone Joint Surg Am       Date:  2000-11       Impact factor: 5.284

2.  The price of pathology: is screening all breast reduction specimens cost effective?

Authors:  Peter F Koltz; John A Girotto
Journal:  Plast Reconstr Surg       Date:  2010-05       Impact factor: 4.730

3.  Necessity of routine pathological examination after surgical excision of wrist ganglions.

Authors:  Thierry G Guitton; Roderick H van Leerdam; David Ring
Journal:  J Hand Surg Am       Date:  2010-05-15       Impact factor: 2.230

4.  Occult carcinoma in 866 reduction mammaplasties: preserving the choice of lumpectomy.

Authors:  Sheri Slezak; Rachel Bluebond-Langner
Journal:  Plast Reconstr Surg       Date:  2011-02       Impact factor: 4.730

5.  Use of routine histologic evaluation of carpal ganglions.

Authors:  Kathleen McKeon; Martin I Boyer; Charles A Goldfarb
Journal:  J Hand Surg Am       Date:  2006-02       Impact factor: 2.230

Review 6.  Recommendations for reporting cost-effectiveness analyses. Panel on Cost-Effectiveness in Health and Medicine.

Authors:  J E Siegel; M C Weinstein; L B Russell; M R Gold
Journal:  JAMA       Date:  1996 Oct 23-30       Impact factor: 56.272

7.  Should we routinely analyze reduction mammaplasty specimens?

Authors:  Päivi A Merkkola-von Schantz; Tiina A Jahkola; Leena A Krogerus; Katja S Hukkinen; Susanna Mc Kauhanen
Journal:  J Plast Reconstr Aesthet Surg       Date:  2016-11-10       Impact factor: 2.740

8.  Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens.

Authors:  Pedro Luiz Serrano Usón Junior; Donato Callegaro Filho; Diogo Diniz Gomes Bugano; Felipe Correa Geyer; Marcus Vinicius de Nigro Corpa; Paulo David Scatena Gonçalves; Sergio Daniel Simon; Rafael Aliosha Kaliks
Journal:  Pathol Oncol Res       Date:  2017-04-08       Impact factor: 3.201

9.  Carcinoma and atypical hyperplasia in reduction mammaplasty: increased sampling leads to increased detection. A prospective study.

Authors:  Abiy B Ambaye; Susan E MacLennan; Andrew J Goodwin; Thomas Suppan; Shelly Naud; Donald L Weaver
Journal:  Plast Reconstr Surg       Date:  2009-11       Impact factor: 4.730

10.  Incidence of precancerous lesions in breast reduction tissue: a pathologic review of 562 consecutive patients.

Authors:  Clancy J Clark; Susan Whang; Keith T Paige
Journal:  Plast Reconstr Surg       Date:  2009-10       Impact factor: 4.730

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.