| Literature DB >> 307184 |
Abstract
The Ca2+ -sensitive bioluminescent protein aequorin was microinjected into cells of frog atrial trabeculae to study intracellular calcium transients associated with excitation-contraction coupling. The amplitude of the aequorin signal increased with extracellular Ca2+ concentration and stimulus frequency, but decreased with stretch. Isoprenaline and acetylstrophanthidin both increased the amplitude, but had strikingly different effects on the time course of the signal.Entities:
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Year: 1978 PMID: 307184 DOI: 10.1038/273509a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962