Literature DB >> 30716362

The role of necroptosis in cancer: A double-edged sword?

Xia Qin1, Dan Ma2, Ye-Xiong Tan3, Hong-Yang Wang4, Zhenyu Cai5.   

Abstract

Necroptosis is a programmed, caspase-independent cell death that is morphologically similar to necrosis. Unlike apoptosis, necroptosis evokes inflammatory responses by releasing damage-associated molecular patterns. Recent studies suggest that tumor undergoes necroptosis in vivo and necroptosis has pro- or anti-tumoral effects in cancer development and progression. Furthermore, triggering necroptosis in tumor cells has been explored as a potential therapeutic strategy against cancer. Here, we will review the recent research progress of necroptosis in conferring anti- or pro-tumoral effects and its potential application in cancer therapy.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer; MLKL; Metastasis; Necroptosis; RIPK3

Mesh：

Year:  2019        PMID： 30716362     DOI： 10.1016/j.bbcan.2019.01.006

Source DB:  PubMed          Journal:  Biochim Biophys Acta Rev Cancer        ISSN： 0304-419X            Impact factor:   10.680


  26 in total

1.  Identification and Verification of Necroptosis-Related Gene Signature With Prognosis and Tumor Immune Microenvironment in Ovarian Cancer.

Authors:  Zitao Wang; Ganhong Chen; Fangfang Dai; Shiyi Liu; Wei Hu; Yanxiang Cheng
Journal:  Front Immunol       Date:  2022-06-24       Impact factor: 8.786

Review 2.  Understanding Necroptosis in Pancreatic Diseases.

Authors:  Ru He; Zhengfeng Wang; Shi Dong; Zhou Chen; Wence Zhou
Journal:  Biomolecules       Date:  2022-06-13

Review 3.  Which cell death modality wins the contest for photodynamic therapy of cancer?

Authors:  Maria Vedunova; Dmitri V Krysko; Tatiana Mishchenko; Irina Balalaeva; Anastasia Gorokhova
Journal:  Cell Death Dis       Date:  2022-05-13       Impact factor: 9.685

4.  Necroptotic astrocytes contribute to maintaining stemness of disseminated medulloblastoma through CCL2 secretion.

Authors:  Hailong Liu; Youliang Sun; Jenny A O'Brien; Janusz Franco-Barraza; Xueling Qi; Hongyu Yuan; Wei Jin; Junping Zhang; Chunyu Gu; Zhenyu Zhao; Chunjiang Yu; Shiyu Feng; Xinguang Yu
Journal:  Neuro Oncol       Date:  2020-05-15       Impact factor: 12.300

5.  Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy - potential markers for predicting breast cancer recurrence?

Authors:  Anna Rothammer; Eva K Sage; Caroline Werner; Stephanie E Combs; Gabriele Multhoff
Journal:  Radiat Oncol       Date:  2019-05-10       Impact factor: 3.481

Review 6.  Necroptosis in Cholangiocarcinoma.

Authors:  Samantha Sarcognato; Iris E M de Jong; Luca Fabris; Massimiliano Cadamuro; Maria Guido
Journal:  Cells       Date:  2020-04-15       Impact factor: 6.600

Review 7.  Molecular mechanisms of cell death in neurological diseases.

Authors:  Diane Moujalled; Andreas Strasser; Jeffrey R Liddell
Journal:  Cell Death Differ       Date:  2021-06-07       Impact factor: 15.828

8.  MLKL-dependent epithelial-to-mesenchymal transition in nasopharyngeal carcinoma: a novel finding and avenues for future research.

Authors:  Tristan Tham
Journal:  Ann Transl Med       Date:  2020-03

Review 9.  Current translational potential and underlying molecular mechanisms of necroptosis.

Authors:  Tamás Molnár; Anett Mázló; Vera Tslaf; Attila Gábor Szöllősi; Gabriella Emri; Gábor Koncz
Journal:  Cell Death Dis       Date:  2019-11-12       Impact factor: 8.469

Review 10.  Necroptosis in Intestinal Inflammation and Cancer: New Concepts and Therapeutic Perspectives.

Authors:  Anna Negroni; Eleonora Colantoni; Salvatore Cucchiara; Laura Stronati
Journal:  Biomolecules       Date:  2020-10-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.