Literature DB >> 30712977

Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.

Andrew P Koutnik1, Dominic P D'Agostino1, Brendan Egan2.   

Abstract

The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  acetoacetate; atrophy; cachexia; inflammation; muscle protein breakdown; β-hydroxybutyrate

Mesh：

Substances：

Year:  2019        PMID： 30712977     DOI： 10.1016/j.tem.2019.01.006

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  17 in total

Review 1.  Exercise-induced muscle damage: mechanism, assessment and nutritional factors to accelerate recovery.

Authors:  I Markus; K Constantini; J R Hoffman; S Bartolomei; Yftach Gepner
Journal:  Eur J Appl Physiol       Date:  2021-01-08       Impact factor: 3.078

2.  Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes.

Authors:  Rainer J Klement; Nanina Brehm; Reinhart A Sweeney
Journal:  Med Oncol       Date:  2020-01-11       Impact factor: 3.064

Review 3.  Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.

Authors:  Mark Evans; Tyler S McClure; Andrew P Koutnik; Brendan Egan
Journal:  Sports Med       Date:  2022-10-10       Impact factor: 11.928

Review 4.  Exercise as a therapy for cancer-induced muscle wasting.

Authors:  Jessica L Halle; Brittany R Counts; James A Carson
Journal:  Sports Med Health Sci       Date:  2020-12-03

5.  A ketogenic diet exerts beneficial effects on body composition of cancer patients during radiotherapy: An interim analysis of the KETOCOMP study.

Authors:  Rainer J Klement; Gabriele Schäfer; Reinhart A Sweeney
Journal:  J Tradit Complement Med       Date:  2019-03-21

Review 6.  From bedside to battlefield: intersection of ketone body mechanisms in geroscience with military resilience.

Authors:  Brianna J Stubbs; Andrew P Koutnik; Jeff S Volek; John C Newman
Journal:  Geroscience       Date:  2020-10-02       Impact factor: 7.713

7.  Ketogenic diets, physical activity and body composition: a review.

Authors:  Damoon Ashtary-Larky; Reza Bagheri; Hoda Bavi; Julien S Baker; Tatiana Moro; Laura Mancin; Antonio Paoli
Journal:  Br J Nutr       Date:  2021-07-12       Impact factor: 4.125

Review 8.  Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections.

Authors:  Brianna J Stubbs; Andrew P Koutnik; Emily L Goldberg; Vaibhav Upadhyay; Peter J Turnbaugh; Eric Verdin; John C Newman
Journal:  Med (N Y)       Date:  2020-07-15

9.  Multiplatform Urinary Metabolomics Profiling to Discriminate Cachectic from Non-Cachectic Colorectal Cancer Patients: Pilot Results from the ColoCare Study.

Authors:  Jennifer Ose; Biljana Gigic; Tengda Lin; David B Liesenfeld; Jürgen Böhm; Johanna Nattenmüller; Dominique Scherer; Lin Zielske; Petra Schrotz-King; Nina Habermann; Heather M Ochs-Balcom; Anita R Peoples; Sheetal Hardikar; Christopher I Li; David Shibata; Jane Figueiredo; Adetunji T Toriola; Erin M Siegel; Stephanie Schmit; Martin Schneider; Alexis Ulrich; Hans-Ulrich Kauczor; Cornelia M Ulrich
Journal:  Metabolites       Date:  2019-09-06

10.  Effects of an Exogenous Ketone Supplement on Five-Kilometer Running Performance.

Authors:  Philip J Prins; Andrew P Koutnik; Dominic P D'Agostino; Christopher Q Rogers; Jacob F Seibert; Jillian A Breckenridge; Daniel S Jackson; Edward J Ryan; Jeffrey D Buxton; Dana L Ault
Journal:  J Hum Kinet       Date:  2020-03-31       Impact factor: 2.193
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