Bone marrow aspiration concentrate and platelet-rich plasma in the treatment of knee osteoarthritis: A report of three cases.

This paper presents the cases of 3 females with knee osteoarthritis. All 3 received a single bone marrow aspiration concentrate (BMAC) injection followed one month later by a platelet-rich plasma (PRP) injection. Compared with the baseline values, pain and functionality scores improved in all the patients. The aim of presenting these cases is to highlight that the combined use of intra-articular BMAC and PRP treatments may have positive effects on pain, functional status and quality of life in patients with knee osteoarthritis.