Literature DB >> 30712393

Physician attitudes about non-medical switching to biosimilars: results from an online physician survey in the United States.

A Teeple1, L A Ellis1, L Huff2, C Reynolds2, S Ginsburg3, L Howard4, D Walls5, J R Curtis6.   

Abstract

OBJECTIVE: This study was designed to understand the level of familiarity of US rheumatologists, gastroenterologists and dermatologists with biosimilar therapies, their experience with non-medical switching (switching medications for reasons unrelated to patient health) of patients between biologics and their attitudes towards switching from a biologic to a biosimilar.
METHODS: A total of 297 US physicians who currently prescribe biologics for their patients completed a 15-minute online survey. Rheumatologists, dermatologists and gastroenterologists were included.
RESULTS: The majority of physicians (84%) did not want stable patients undergoing a non-medical switch to a biosimilar. While 60% of physicians believed non-medical switching to biosimilars may have a positive impact on healthcare system costs, multiple negative impacts were also expected. A majority of physicians anticipated a negative impact on patient mental health (59%), treatment efficacy (57%), patient safety (53%) and physician office management (60%).
CONCLUSIONS: The majority of physicians had concerns regarding non-medical switching to biosimilars and the impact such switching would have on patient care and physician practice.

Entities:  

Keywords:  Biologic therapies; attitudes; biosimilar; dermatologists; gastroenterologists; physician; rheumatologists

Mesh:

Substances:

Year:  2019        PMID: 30712393     DOI: 10.1080/03007995.2019.1571296

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  14 in total

1.  Budget Impact Analysis of Switching to Rituximab's Biosimilar in Rheumatology and Cancer in 13 Countries Within the Middle East and North Africa.

Authors:  Ammar Almaaytah
Journal:  Clinicoecon Outcomes Res       Date:  2020-09-15

2.  Knowledge, Attitudes and Practice of Healthcare Providers, Healthcare Regulatory Practitioners and Patients Toward Biosimilars in China: Insights From a Nationwide Survey.

Authors:  Yang Hu; Zaiwei Song; Dan Jiang; Lin Zhuo; Yinchu Cheng; Rongsheng Zhao
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

3.  Knowledge of biosimilars and perceptions of the naming conventions for biosimilar products in clinical practice in the United States.

Authors:  Marianna Olave; Criswell Lavery; Charles E Leonard; Vincent Lo Re; Judy A Shea; Jonathan Kay; Joshua F Baker
Journal:  Drugs Ther Perspect       Date:  2021-06-08

4.  Switching and Discontinuation Patterns Among Patients Stable on Originator Infliximab Who Switched to an Infliximab Biosimilar or Remained on Originator Infliximab.

Authors:  Timothy Fitzgerald; Richard Melsheimer; Marie-Hélène Lafeuille; Patrick Lefebvre; Laura Morrison; Kimberly Woodruff; Iris Lin; Bruno Emond
Journal:  Biologics       Date:  2021-01-06

5.  Patient perspectives on the British Columbia Biosimilars Initiative: a qualitative descriptive study.

Authors:  Caitlin Chew; Magda Aguiar; Nick Bansback; Michael R Law; Mark Harrison
Journal:  Rheumatol Int       Date:  2021-05-07       Impact factor: 3.580

Review 6.  The Automatic Substitution of Biosimilars: Definitions of Interchangeability are not Interchangeable.

Authors:  Anita Afzali; Daniel Furtner; Richard Melsheimer; Philip J Molloy
Journal:  Adv Ther       Date:  2021-03-21       Impact factor: 3.845

7.  Interchangeability of biosimilars: A study of expert views and visions regarding the science and substitution.

Authors:  Louise C Druedahl; Sofia Kälvemark Sporrong; Timo Minssen; Hans Hoogland; Marie Louise De Bruin; Marco van de Weert; Anna Birna Almarsdóttir
Journal:  PLoS One       Date:  2022-01-11       Impact factor: 3.240

8.  Is There Any Research Evidence Beyond Surveys and Opinion Polls on Automatic Substitution of Biological Medicines? A Systematic Review.

Authors:  Hanna M Tolonen; Jenni Falck; Pekka Kurki; Päivi Ruokoniemi; Katri Hämeen-Anttila; Kenneth M Shermock; Marja Airaksinen
Journal:  BioDrugs       Date:  2021-08-16       Impact factor: 5.807

Review 9.  An Update Review of Biosimilars of Adalimumab in Psoriasis - Bioequivalence and Interchangeability.

Authors:  Xin Zhou; Zhuo Chen; Xinling Bi
Journal:  Drug Des Devel Ther       Date:  2021-07-08       Impact factor: 4.162

Review 10.  Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology?

Authors:  Roy Fleischmann; Vipul Jairath; Eduardo Mysler; Dave Nicholls; Paul Declerck
Journal:  Rheumatol Ther       Date:  2020-01-16
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