Barbara Caravale1, Lena Herich2, Stefania Zoia3, Luca Capone4, Fabio Voller5, Marco Carrozzi6, Valeria Chiandotto7, Umberto Balottin8, Maria Lacchei9, Ileana Croci10, Marina Cuttini11. 1. Department of Developmental and Social Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185, Rome, Italy. Electronic address: barbara.caravale@uniroma1.it. 2. Clinical Care and Management Innovation Research Area, Bambino Gesù Children's Hospital, IRCCS, Viale Ferdinando Baldelli 41, 00146, Rome, Italy. Electronic address: lena.herich@opbg.net. 3. Struttura Complessa Tutela Salute Bambini Adolescenti Donne Famiglia, Azienda Sanitaria Universitaria Integrata di Trieste, Via Giovanni Sai 7, 34128, Trieste, Italy. Electronic address: stefania.zoia@asuits.sanita.fvg.it. 4. Child Neuropsychiatry Unit, IRCCS Mondino Foundation, Via Mondino 2, 27100, Pavia, Italy. Electronic address: luca.capone@mondino.it. 5. Epidemiology Unit, Regional Health Agency of Tuscany, Via Pietro Dazzi 1, 50141, Florence, Italy. Electronic address: fabio.voller@ars.toscana.it. 6. Department of Neuroscience, Burlo Garofolo Hospital, IRCCS, Via dell'Istria 65/1, 34127, Trieste, Italy. Electronic address: marco.carrozzi@burlo.trieste.it. 7. Neonatal Intensive Care Unit, S. Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100, Udine, Italy. Electronic address: chiandotto.valeria@aoud.sanita.fvg.it. 8. Department of Brain and Behavioral Sciences, University of Pavia, Via Bassi 21, 27100, Pavia, Italy; Child Neuropsychiatry Unit, IRCCS Mondino Foundation, Via Mondino 2, 27100, Pavia, Italy. Electronic address: umberto.balottin@unipv.it. 9. Clinical Care and Management Innovation Research Area, Bambino Gesù Children's Hospital, IRCCS, Viale Ferdinando Baldelli 41, 00146, Rome, Italy. Electronic address: maria.lacchei@opbg.net. 10. Clinical Care and Management Innovation Research Area, Bambino Gesù Children's Hospital, IRCCS, Viale Ferdinando Baldelli 41, 00146, Rome, Italy. Electronic address: ileana.croci@opbg.net. 11. Clinical Care and Management Innovation Research Area, Bambino Gesù Children's Hospital, IRCCS, Viale Ferdinando Baldelli 41, 00146, Rome, Italy. Electronic address: marina.cuttini@opbg.net.
Abstract
BACKGROUND: Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that involves difficulties in goal-directed motor coordination, with ineffective control of fine and gross motor movements in the absence of sensory impairment or neurological condition. DCD is frequently reported in children born very preterm (VP) who survive without CP. AIMS: To measure the risk of DCD at school age in a large area-based cohort of VP children and general population controls, adjusting for gender, birth weight by gestational age and age at assessment. METHODS: VP children (N = 608) were part of a prospective cohort study in Italy. Controls (N = 370) were participants in the DCDQ-Italian validation study in the same age range. The Italian version of Developmental Coordination Disorder Questionnaire (DCDQ-Italian) was used to measure the performances in motor coordination during ordinary activities from the parental point of view. Multivariable regression analysis was used to obtain adjusted risk ratios of screening positive for DCD. RESULTS: VP children had scores significantly lower than peers, and about 30% of them appeared at risk of DCD using the 15th percentile cut-off of the Italian validation study. Birth-weight <10th percentile for gestational age and male gender were significant predictors. A slight trend effect was present, with extremely preterm children (<28 weeks gestation) showing the highest risk. CONCLUSIONS: Our study confirmed the higher DCD risk in VP children, particularly when males and SGA.
BACKGROUND:Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that involves difficulties in goal-directed motor coordination, with ineffective control of fine and gross motor movements in the absence of sensory impairment or neurological condition. DCD is frequently reported in children born very preterm (VP) who survive without CP. AIMS: To measure the risk of DCD at school age in a large area-based cohort of VP children and general population controls, adjusting for gender, birth weight by gestational age and age at assessment. METHODS: VP children (N = 608) were part of a prospective cohort study in Italy. Controls (N = 370) were participants in the DCDQ-Italian validation study in the same age range. The Italian version of Developmental Coordination Disorder Questionnaire (DCDQ-Italian) was used to measure the performances in motor coordination during ordinary activities from the parental point of view. Multivariable regression analysis was used to obtain adjusted risk ratios of screening positive for DCD. RESULTS: VP children had scores significantly lower than peers, and about 30% of them appeared at risk of DCD using the 15th percentile cut-off of the Italian validation study. Birth-weight <10th percentile for gestational age and male gender were significant predictors. A slight trend effect was present, with extremely preterm children (<28 weeks gestation) showing the highest risk. CONCLUSIONS: Our study confirmed the higher DCD risk in VP children, particularly when males and SGA.
Authors: Rebeca Montes-Montes; Laura Delgado-Lobete; Javier Pereira; Marina M Schoemaker; Sergio Santos-Del-Riego; Thais Pousada Journal: Int J Environ Res Public Health Date: 2020-01-15 Impact factor: 3.390