Literature DB >> 30711110

Comprehensive structural characterization of phenolics in litchi pulp using tandem mass spectral molecular networking.

Qiang Lyu1, Ting-Hao Kuo2, Chongde Sun3, Kunsong Chen3, Cheng-Chih Hsu4, Xian Li5.   

Abstract

Phenolic compounds are a large class of plant secondary metabolites with various health-promoting effects, and are known for their structural diversity. Therefore, high efficiency characterization of phenolic profiles is of key importance in identifying their potential bioactivity. In the present study, Global Natural Products Social (GNPS) Molecular Networking was applied to trace the phenolic compounds in plants, which allowed the characterization of 9 procyanidins and 11 flavonoid glycosides (di-, tri-, or tetra-saccharides of kaempferol, quercetin, isorhamnetin and myricetin) in litchi pulp extracts. Six compounds were reported for the first time in litchi pulp. In addition, quercetin-3-O-rutinoside-(1 → 2)-O-rhamnoside, the most abundant flavonoid glycoside in litchi pulp, was proved to have considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Keywords:  (–)-Epicatechin (PubChem CID: 72276); GNPS; Isorhamnetin-3-O-rutinoside (PubChem CID: 5481663); Kaempferol-3-O-rutinoside (PubChem CID: 5318767); LC-ESI-MS; Litchi chinensis pulp; Phenolic compounds identification; Procyanidin B2 (PubChem CID: 122738); Quercetin-3-O-rutinoside (PubChem CID: 5280805); α-Glucosidase inhibitory activity

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Year:  2019        PMID: 30711110     DOI: 10.1016/j.foodchem.2019.01.001

Source DB:  PubMed          Journal:  Food Chem        ISSN: 0308-8146            Impact factor:   7.514


  3 in total

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  3 in total

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