Literature DB >> 30710123

How an activation signal is transmitted through an excitatory receptor.

Karen J Gregory.   

Abstract

Entities:  

Keywords:  Neuroscience; Structural biology

Mesh：

Substances：

Year:  2019        PMID： 30710123     DOI： 10.1038/d41586-018-07885-x

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  8 in total

1.  Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).

Authors:  John A Christopher; Sarah J Aves; Kirstie A Bennett; Andrew S Doré; James C Errey; Ali Jazayeri; Fiona H Marshall; Krzysztof Okrasa; Maria J Serrano-Vega; Benjamin G Tehan; Giselle R Wiggin; Miles Congreve
Journal:  J Med Chem       Date:  2015-08-12       Impact factor: 7.446

2.  Interdomain movements in metabotropic glutamate receptor activation.

Authors:  Siluo Huang; Jianhua Cao; Ming Jiang; Gilles Labesse; Jianfeng Liu; Jean-Philippe Pin; Philippe Rondard
Journal:  Proc Natl Acad Sci U S A       Date:  2011-09-06       Impact factor: 11.205

3.  Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.

Authors:  Li Xue; Xavier Rovira; Pauline Scholler; Han Zhao; Jianfeng Liu; Jean-Philippe Pin; Philippe Rondard
Journal:  Nat Chem Biol       Date:  2014-12-15       Impact factor: 15.040

4.  Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.

Authors:  Driss El Moustaine; Sébastien Granier; Etienne Doumazane; Pauline Scholler; Rita Rahmeh; Patrick Bron; Bernard Mouillac; Jean-Louis Banères; Philippe Rondard; Jean-Philippe Pin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-17       Impact factor: 11.205

5.  Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.

Authors:  Huixian Wu; Chong Wang; Karen J Gregory; Gye Won Han; Hyekyung P Cho; Yan Xia; Colleen M Niswender; Vsevolod Katritch; Jens Meiler; Vadim Cherezov; P Jeffrey Conn; Raymond C Stevens
Journal:  Science       Date:  2014-03-06       Impact factor: 47.728

6.  Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Authors:  Andrew S Doré; Krzysztof Okrasa; Jayesh C Patel; Maria Serrano-Vega; Kirstie Bennett; Robert M Cooke; James C Errey; Ali Jazayeri; Samir Khan; Ben Tehan; Malcolm Weir; Giselle R Wiggin; Fiona H Marshall
Journal:  Nature       Date:  2014-07-06       Impact factor: 49.962

Review 7.  Trends in GPCR drug discovery: new agents, targets and indications.

Authors:  Alexander S Hauser; Misty M Attwood; Mathias Rask-Andersen; Helgi B Schiöth; David E Gloriam
Journal:  Nat Rev Drug Discov       Date:  2017-10-27       Impact factor: 84.694

8.  Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

Authors:  Junke Liu; Zongyong Zhang; Philippe Rondard; Siluo Huang; Jianfeng Liu; Jean-Philippe Pin; David Moreno-Delgado; James Ar Dalton; Xavier Rovira; Ana Trapero; Cyril Goudet; Amadeu Llebaria; Jesús Giraldo; Qilin Yuan
Journal:  Elife       Date:  2017-08-10       Impact factor: 8.140
  8 in total

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